Terekhina A I, Kruglova O N
Farmakol Toksikol. 1987 May-Jun;50(3):69-70.
Administration of piracetam to infantile rats in a daily dose of 100 mg/kg for 10 days caused acceleration of sexual maturation of females and a slight delay of maturation of males. Antenatal administration of the same dose of piracetam exerted a depressive action on the development of the organs of the reproductive system in males from the offspring with a simultaneous increase in the pituitary gonadotropic activity.
以每日100毫克/千克的剂量给幼鼠注射吡拉西坦,持续10天,会导致雌性幼鼠性成熟加速,雄性幼鼠成熟稍有延迟。产前给予相同剂量的吡拉西坦,对后代雄性生殖系统器官的发育产生抑制作用,同时垂体促性腺活性增加。