猪心磷脂对心肌AMP脱氨酶的调节作用。
Regulatory effect of pig heart phospholipids on heart muscle AMP-deaminase.
作者信息
Purzycka-Preis J, Zydowo M M
出版信息
Int J Biochem. 1987;19(6):565-8. doi: 10.1016/0020-711x(87)90142-x.
PMID:3609447
Abstract
AMP-deaminase purified from pig heart has been found to be activated by liposomes prepared from phospholipids extracted from pig heart mitochondria, microsomes and cytoplasm, as well as by intact microsomes. The activation by phospholipids occurred only in the presence of ATP and after the enzyme had been preincubated with liposomes for 30 min. Liposomes prepared from cardiolipin displayed an inhibitory effect on pig heart AMP-deaminase.
摘要
已发现从猪心纯化的AMP脱氨酶可被由从猪心线粒体、微粒体和细胞质中提取的磷脂制备的脂质体以及完整的微粒体激活。磷脂的激活仅在ATP存在下且酶与脂质体预孵育30分钟后发生。由心磷脂制备的脂质体对猪心AMP脱氨酶显示出抑制作用。
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