磷脂酰胆碱和鞘磷脂对猪脑腺苷酸脱氨酶作用的多样性。
Diversity of the effect of phosphatidylcholine and sphingomyelin on adenylate deaminase from pig brain.
作者信息
Woźniak M, Purzycka-Preis J, Kossowska E, Zydowo M M
机构信息
Department of Biochemistry, Academic Medical School, Gdańsk, Poland.
出版信息
Acta Biochim Pol. 1987;34(3):285-90.
PMID:3687300
Abstract
Liposomes made of sphingomyelin were found to inhibit both ATP-activated and non-activated AMP deaminase from pig brain, in contrast to liposomes made of egg yolk phosphatidylcholine which exhibited an activating effect on the ATP-activated enzyme, being without effect on AMP deaminase in the absence of ATP. Dioleoylphosphatidylcholine exerted a similar effect as egg yolk phosphatidylcholine but dipalmitoylphosphatidylcholine was without effect.
摘要
结果发现，由鞘磷脂制成的脂质体能够抑制来自猪脑的ATP激活型和非激活型AMP脱氨酶，而由蛋黄磷脂酰胆碱制成的脂质体对ATP激活型酶具有激活作用，在无ATP的情况下对AMP脱氨酶无作用。二油酰磷脂酰胆碱发挥了与蛋黄磷脂酰胆碱类似的作用，但二棕榈酰磷脂酰胆碱则无作用。
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引用本文的文献
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