Koh Shizuka, Inoue Yasushi, Ochi Shintaro, Takai Yoshihiro, Maeda Naoyuki, Nishida Kohji
Department of Innovative Visual Science, Osaka University Graduate School of Medicine, Osaka, Japan; Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.
Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan; Inoue Eye Clinic, Okayama, Japan.
Am J Ophthalmol. 2017 Sep;181:71-78. doi: 10.1016/j.ajo.2017.06.022. Epub 2017 Jul 1.
To investigate visual function and optical quality in eyes with epiphora undergoing lacrimal passage intubation.
Prospective case series.
Thirty-four eyes of 30 patients with lacrimal passage obstruction were enrolled. Before and 1 month after lacrimal passage intubation, functional visual acuity (FVA), higher-order aberrations (HOAs), lower tear meniscus, and tear clearance were assessed. An FVA measurement system was used to examine changes in continuous visual acuity (VA) over time, and visual function parameters such as FVA, visual maintenance ratio, and blink frequency were obtained. Sequential ocular HOAs were measured for 10 seconds after the blink using a wavefront sensor. Aberration data were analyzed in the central 4 mm for coma-like, spherical-like, and total HOAs. Fluctuation and stability indices of the total HOAs over time were calculated. Lower tear meniscus was assessed by anterior segment optical coherence tomography.
After lacrimal passage intubation, visual function significantly improved, as indicated by improved FVA (P = .003) and visual maintenance ratio (P < .001). Blink frequency decreased significantly after treatment (P = .01). Optical quality significantly improved, as indicated by a decrease in coma-like aberrations (P = .003), spherical-like aberrations (P = .018), and total HOAs (P = .001). Stability index increased (P < .001) and fluctuation index decreased (P = .019), and tear meniscus dimension decreased (P < .001).
Lacrimal passage intubation for eyes with epiphora significantly improved visual function and optical quality via patency of the lacrimal passage.
研究接受泪道插管术的溢泪患者的视功能和光学质量。
前瞻性病例系列研究。
纳入30例泪道阻塞患者的34只眼。在泪道插管术前和术后1个月，评估功能性视力（FVA）、高阶像差（HOAs）、下泪液弯月面和泪液清除情况。使用FVA测量系统检查连续视力（VA）随时间的变化，并获得FVA、视觉维持率和眨眼频率等视功能参数。使用波前传感器在眨眼后测量10秒的连续眼高阶像差。对中央4mm区域的像差数据进行分析，以获取类彗差、类球差和总高阶像差。计算总高阶像差随时间的波动和稳定性指数。通过眼前节光学相干断层扫描评估下泪液弯月面。
泪道插管术后，视功能显著改善，表现为FVA提高（P = .003）和视觉维持率提高（P < .001）。治疗后眨眼频率显著降低（P = .01）。光学质量显著改善，表现为类彗差降低（P = .003）、类球差降低（P = .018）和总高阶像差降低（P = .001）。稳定性指数增加（P < .001），波动指数降低（P = .019），泪液弯月面尺寸减小（P < .001）。
泪道插管术通过使泪道通畅，显著改善了溢泪患者的视功能和光学质量。
