Yazıcıoglu Titap, Oklar Murat, Ozkoyuncu Kocabas Dilara
Department of Ophthalmology, University of Health Sciences, Kartal Dr. Lutfi Kirdar City Hospital, Istanbul, Turkey.
Department of Ophthalmology, TOBB Economics and Technology University, Ankara, Turkey.
Int Ophthalmol. 2025 Sep 1;45(1):370. doi: 10.1007/s10792-025-03725-w.
To assess the impact of external dacryocystorhinostomy (EXT-DCR) on optical quality in patients with primary acquired nasolacrimal duct obstruction (PANDO) by evaluating changes in corneal higher-order aberrations (HOAs) and key optical quality parameters, including modulation transfer function (MTF) and point spread function (PSF).
This retrospective study included 26 eyes of 26 patients who underwent unilateral EXT-DCR for PANDO. Preoperative and 6-month postoperative assessments included best-corrected visual acuity (BCVA), manifest refraction spherical equivalent (MRSE), and epiphora severity (Munk score, fluorescein dye disappearance test [FDDT]). HOAs, MTF, and PSF were analyzed at 3 mm and 6 mm pupil diameters using Sirius corneal topography. Paired t-tests, Wilcoxon signed-rank tests, and Spearman correlation analyses were used.
Postoperatively, HOA significantly decreased at 3 mm (0.183 ± 0.160 - 0.128 ± 0.058 µm, p = 0.020) and 6 mm (0.744 ± 0.350 - 0.641 ± 0.271 µm, p = 0.039). Spherical aberration at 6 mm also significantly decreased (- 0.237 ± 0.203 - - 0.194 ± 0.247 µm, p = 0.032). MTF and PSF values showed no significant postoperative changes (p > 0.05). Correlation analysis of Δ values (preoperative-postoperative changes) revealed significant associations between reductions in Munk/FDDT scores and improvements in HOA and spherical aberrations (p < 0.05).
EXT-DCR may significantly improve optical quality by reducing HOAs and spherical aberrations. The correlation between epiphora resolution and optical quality suggests that stabilizing the tear film plays a key role in reducing optical distortions. While MTF and PSF values did not show significant changes, further studies with larger cohorts and advanced imaging techniques are warranted to explore the broader impact of lacrimal surgery on visual function and contrast sensitivity parameters.
通过评估角膜高阶像差(HOA)以及包括调制传递函数(MTF)和点扩散函数(PSF)在内的关键光学质量参数的变化,来评估外路泪囊鼻腔吻合术(EXT-DCR)对原发性获得性鼻泪管阻塞(PANDO)患者光学质量的影响。
这项回顾性研究纳入了26例因PANDO接受单侧EXT-DCR手术的患者的26只眼。术前和术后6个月的评估包括最佳矫正视力(BCVA)、显验光球镜等效度(MRSE)和溢泪严重程度(蒙克评分、荧光素染料消失试验[FDDT])。使用Sirius角膜地形图仪在3mm和6mm瞳孔直径下分析HOA、MTF和PSF。采用配对t检验、Wilcoxon符号秩检验和Spearman相关性分析。
术后,3mm(0.183±0.160 - 0.128±0.058µm,p = 0.020)和6mm(0.744±0.350 - 0.641±0.271µm,p = 0.039)处的HOA显著降低。6mm处的球差也显著降低(-0.237±0.203 - -0.194±0.247µm,p = 0.032)。MTF和PSF值术后无显著变化(p>0.05)。Δ值(术前-术后变化)的相关性分析显示,蒙克/FDDT评分降低与HOA和球差改善之间存在显著关联(p<0.05)。
EXT-DCR可能通过降低HOA和球差来显著改善光学质量。溢泪症状缓解与光学质量之间的相关性表明,稳定泪膜在减少光学畸变方面起关键作用。虽然MTF和PSF值没有显示出显著变化,但有必要进行更大样本量的队列研究和采用先进成像技术的进一步研究,以探讨泪道手术对视觉功能和对比敏感度参数的更广泛影响。