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爱泼斯坦-巴尔病毒感染是一个全球性的流行病学问题。

[Epstein-Barr viral infection is a global epidemiological problem].

作者信息

Solomay T V, Semenenko T A

机构信息

Interregional Department No. 1 of the FMBA of Russia; I.I. Mechnikov Research Institute of Vaccines and Serums of the Ministry of Education and Science of Russia.

National Research Center of Epidemiology and Microbiology named after Honorary Academician N.F. Gamaleya of the Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia.

出版信息

Vopr Virusol. 2022 Sep 10;67(4):265-273. doi: 10.36233/0507-4088-122.

Abstract

The number of studies devoted to Epstein-Barr viral infection (EBV infection) has been growing in recent years. However, they all relate to the clinical aspects of this problem. Epidemiology issues remain practically unexplored. A review of domestic and foreign publications has shown that at the present stage there is a high intensity of the epidemic process of EBV infection both in Russia and abroad. The main indicators of unfavorable epidemiological situation are the ubiquitous spread of the pathogen and the increase in the incidence of infectious mononucleosis in recent years. The deterioration of the epidemic situation of EBV infection is influenced by changes in the immunological reactivity of various population groups due to the spread of HIV, HBV, HCV, the causative agent of tuberculosis and SARS-CoV-2. The above makes it possible to classify the problem as a global one and determines the need for the rapid implementation of the system of epidemiological surveillance of EBV infection and optimization of the complex of preventive and anti-epidemic measures. Reducing the burden of EBV is possible only with the consolidated participation of specialists of various profiles.

摘要

近年来,致力于研究爱泼斯坦-巴尔病毒感染(EBV感染)的研究数量一直在增加。然而,这些研究都与该问题的临床方面有关。流行病学问题实际上仍未得到探索。对国内外出版物的回顾表明,现阶段俄罗斯和国外EBV感染的流行过程强度都很高。不利的流行病学状况的主要指标是病原体的普遍传播以及近年来传染性单核细胞增多症发病率的增加。由于HIV、HBV、HCV、结核病病原体和SARS-CoV-2的传播,不同人群免疫反应性的变化影响了EBV感染疫情的恶化。上述情况使得将该问题归类为全球性问题成为可能,并确定了迅速实施EBV感染流行病学监测系统以及优化预防和抗疫措施组合的必要性。只有各类专业人员共同参与,才有可能减轻EBV的负担。

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