IPS Universitaria, Universidad de Antioquia, Medellín, Colombia.
Centros Especializados de San Vicente Fundación, Rionegro, Antioquia, Colombia.
Medwave. 2022 Sep 13;22(8):e002564. doi: 10.5867/medwave.2022.08.002564.
Although psoriasis burden and treatment have been well characterized in developed countries, there are scarce in-depth epidemiological studies in Latin American countries.
To describe the sociodemographic and clinical features and the economic burden of psoriasis among children and adult patients from Colombia.
This cross-sectional study included patients from dermatology private practice offices, health provider institutions and hospitals in seven Colombian cities. We collected data on disease distribution, weight, height, body mass index, waist-hip ratio, disease severity, therapy, personal history of comorbidities, and direct costs. Multiple logistic regression analyses were conducted to assess the associations between severity scales and sociodemographic and clinical variables.
Two-hundred-three patients (43.8% women, 56.2% men) with an age range between 7 to 89 years old were included. The main subtype was psoriasis vulgaris and mean age of diagnosis was 37.1 years. The most common comorbidities were obesity, hypertension, psoriatic arthritis, dyslipidemia and diabetes. Women had a significant increased odds of presenting with psoriatic arthritis. Body-mass-index and hypertension were significantly associated with a higher psoriasis severity, whereas being female and non-obese was associated with a lower risk. A third of the patients had a family history of psoriasis and sleeping disorders. Forty-one percent of participants either had no income or had an income below 224 US dollars per month and >20% of their income was spent on their disease.
This study is supported by robust scientific data and contributes to understanding the burden of psoriasis in Latin America. This study adds well-supported data through an in-depth clinical and economical characterization of Colombian children and adult patients with psoriasis and shows the high impact and burden of the disease on patients and their families.
尽管在发达国家已经很好地描述了银屑病的负担和治疗情况，但在拉丁美洲国家几乎没有深入的流行病学研究。
描述来自哥伦比亚的儿童和成年银屑病患者的社会人口统计学和临床特征以及经济负担。
本横断面研究纳入了来自哥伦比亚七个城市的皮肤科私人诊所、医疗机构和医院的患者。我们收集了疾病分布、体重、身高、体重指数、腰臀比、疾病严重程度、治疗、个人合并症史以及直接费用的数据。采用多因素逻辑回归分析评估严重程度量表与社会人口统计学和临床变量之间的关系。
共纳入了 203 例（43.8%为女性，56.2%为男性）年龄在 7 至 89 岁之间的患者。主要亚型为寻常型银屑病，诊断时的平均年龄为 37.1 岁。最常见的合并症是肥胖症、高血压、银屑病关节炎、血脂异常和糖尿病。女性发生银屑病关节炎的可能性显著增加。体重指数和高血压与银屑病严重程度显著相关，而女性和非肥胖患者的风险较低。三分之一的患者有银屑病家族史和睡眠障碍。41%的参与者没有收入或月收入低于 224 美元，超过 20%的收入用于治疗疾病。
本研究提供了可靠的科学数据，有助于了解拉丁美洲银屑病的负担。本研究通过对哥伦比亚儿童和成年银屑病患者进行深入的临床和经济特征描述，提供了有力的数据支持，并表明该疾病对患者及其家庭的影响和负担很大。
