经囟门光声成像测量活体脑氧合。

Richard and Loan Hill Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, USA.

Department of Neurological Surgery, University of Illinois at Chicago - College of Medicine, Chicago, IL, USA.

Sci Rep. 2022 Sep 13;12(1):15394. doi: 10.1038/s41598-022-19350-x.

The capability of photoacoustic (PA) imaging to measure oxygen saturation through a fontanelle has been demonstrated in large animals in-vivo. We called this method, transfontanelle photoacoustic imaging (TFPAI). A surgically induced 2.5 cm diameter cranial window was created in an adult sheep skull to model the human anterior fontanelle. The performance of the TFPAI has been evaluated by comparing the PA-based predicted results against the gold standard of blood gas analyzer measurements.

光声（PA）成像通过囟门测量氧饱和度的能力已在大型动物体内得到证实。我们称这种方法为经囟门光声成像（TFPAI）。在成年羊颅骨上开一个 2.5 厘米直径的手术诱导颅窗，模拟人类前囟门。通过将基于 PA 的预测结果与血气分析仪测量的金标准进行比较，评估了 TFPAI 的性能。