Janjić Klara, Reisinger Christoph, Kanz Fabian
University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria.
Center for Forensic Medicine, Medical University of Vienna, 1090 Vienna, Austria.
Biology (Basel). 2022 Jul 18;11(7):1071. doi: 10.3390/biology11071071.
Biological clocks set the timing for a large number of essential processes in the living human organism. After death, scientific evidence is required in forensic investigations in order to collect as much information as possible on the death circumstances and personal identifiers of the deceased victim. We summarize the associations between the molecular mechanisms of biological rhythms and forensically relevant aspects, including post-mortem interval and cause of death, entomological findings, sex, age, ethnicity and development. Given their importance during lifetime, biological rhythms could be potential tools to draw conclusions on the death circumstances and the identity of a deceased person by mechanistic investigations of the different biological clocks in a forensic context. This review puts the known effects of biological rhythms on the functions of the human organism in context with potential applications in forensic fields of interest, such as personal identification, entomology as well as the determination of the post-mortem interval and cause of death.
生物钟为人类活体中的大量基本生理过程设定时间。死后,法医调查需要科学证据,以便尽可能多地收集关于死亡情况和死者个人身份识别信息。我们总结了生物节律的分子机制与法医相关方面之间的关联,包括死后间隔时间和死因、昆虫学发现、性别、年龄、种族和发育情况。鉴于生物节律在生命过程中的重要性,通过在法医背景下对不同生物钟进行机制研究,生物节律可能成为推断死亡情况和死者身份的潜在工具。本综述将生物节律对人体机能的已知影响与法医相关领域(如个人身份识别、昆虫学以及死后间隔时间和死因的确定)的潜在应用相结合。