Department of Biology, College of Natural and Computational Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Ethiopian Forestry Development, Central Ethiopia Center, Addis Ababa, Ethiopia.
Nat Prod Res. 2023 Jun;37(11):1816-1821. doi: 10.1080/14786419.2022.2123478. Epub 2022 Sep 14.
is a hemi-parasitic shrub. It is known for treating various health ailments. The aim of this study was to evaluate the antimicrobial activity, toxicity, and chemical characterization of the leaf extracts of collected from the host plant in Ethiopia. The antimicrobial properties of crude extracts obtained with chloroform, ethyl acetate, methanol, and water solvents were assayed against , , and The methanol extract significantly inhibited the growth of and were resistant to any of these solvent extracts. The methanol extract was tested at 175, 550, and 2000 mg/kg body weight doses in white mice and did not reveal any toxicity. The LC-MS qTOF analysis detected flavonoids, phenolic acids, and alkaloids in the crude methanol extract. Further study is needed to investigate the effectiveness of these compounds against .
是一种半寄生灌木。它被用于治疗各种健康疾病。本研究旨在评估从埃塞俄比亚的宿主植物中采集的叶提取物的抗菌活性、毒性和化学成分特征。用氯仿、乙酸乙酯、甲醇和水溶剂获得的粗提取物的抗菌性能对抗、和进行了测定。甲醇提取物显著抑制了和的生长，而对这些溶剂提取物均具有抗性。甲醇提取物以 175、550 和 2000mg/kg 体重剂量在小白鼠中进行了测试，没有显示出任何毒性。LC-MS qTOF 分析检测到粗甲醇提取物中的类黄酮、酚酸和生物碱。需要进一步研究这些化合物对的有效性。
