Duan Xiaomin, Wang Wei, Ma Wenping, Mao Zhenhui, Xing Fangliang, Zhao Xin
Department Radiology-Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.
Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100070, China.
Int J Bioprint. 2022 Apr 29;8(3):555. doi: 10.18063/ijb.v8i3.555. eCollection 2022.
It is technically challenging for pediatric anesthesiologists to use bronchial blocker (BB) to isolate the lungs of infants during thoracoscopic surgery. Further, BB currently sold in the market cannot match the anatomical characteristics of the infants, especially on the right main bronchus. It may easily cause poor exhaustion of the right upper lobe, which leads to interference with the thoracoscopic surgical field. The two dimensional reconstruction data of 124 normal infants' airways were extracted from the medical image database of Beijing Children's Hospital for statistical analysis. After using linear fitting and goodness-of-fit test, a good linear relationship was detected between infant age and various parameters related to aid in designing a new BB for infants (R=0.502). According to the growth and development rate of infants, the DICOM files of airway CT scan of 7 infants aged 30, 60, 90, 120, 180, 270, and 360 days were selected to print non-transparent convex and transparent concave 3D models. The non-transparent convex model was precisely measured to obtain the important parameters for BB design infants only, to complete the design of BB, to generate the sample, and to verify the blocking effect of produced sample in transparent concave three-dimensional (3D) model.
对于小儿麻醉医生而言，在胸腔镜手术期间使用支气管封堵器（BB）来隔离婴儿的肺部在技术上具有挑战性。此外，目前市场上销售的BB无法匹配婴儿的解剖特征，尤其是在右主支气管方面。这可能容易导致右上叶排气不畅，进而干扰胸腔镜手术视野。从北京儿童医院的医学影像数据库中提取了124例正常婴儿气道的二维重建数据进行统计分析。经过线性拟合和拟合优度检验，发现婴儿年龄与有助于设计新型婴儿用BB的各种参数之间存在良好的线性关系（R = 0.502）。根据婴儿的生长发育速度，选择了7例年龄分别为30、60、90、120、180、270和360天的婴儿气道CT扫描的DICOM文件，打印出不透明凸形和透明凹形的3D模型。对不透明凸形模型进行精确测量，以仅获取用于设计婴儿用BB的重要参数，完成BB的设计，生成样品，并在透明凹形三维（3D）模型中验证所生产样品的封堵效果。
