Sano Kenshi, Kuge Atsushi, Kondo Rei, Yamaki Tetsu, Homma Hiroshi, Saito Shinjiro, Sonoda Yukihiko
Department of Neurosurgery Yamagata City Hospital Saiseikan Yamagata Japan.
Department of Emergency Medicine Yamagata City Hospital Saiseikan Yamagata Japan.
Clin Case Rep. 2022 Sep 12;10(9):e6257. doi: 10.1002/ccr3.6257. eCollection 2022 Sep.
Headache is one of the most common symptoms encountered during the postpartum period. The cause may be unknown, or the following illnesses are possible: cervical artery dissection (CAD), reversible posterior cerebral encephalopathy syndrome (PRES), and reversible cerebral vasoconstrictor syndrome (RCVS). It is suggested that they are interrelated and share a similar mechanism such as small vessel endothelial dysfunction, deficiencies in self-regulation, and decreased sympathetic innervation of the posterior circulation. However, there are few reports of neuroradiological findings. We experienced a rare case of multiple postpartum vascular disease occurring at the same time. A 38-year-old woman suddenly developed thunderclap headache after giving birth. She was clear and had no neuropathy. Computed tomography revealed subarachnoid hemorrhage, including the cortical surface of the frontal lobe. Magnetic resonance image fluid-attenuated inversion recovery revealed high-intensity area in the bilateral basal ganglia and right occipital cortex. Angiography showed "string sausage" and extracranial left vertebral artery stenosis, but no aneurysm. Based on the clinical course and neuroradiological findings, we diagnosed her as postpartum vascular disease including CAD, PRES, RCVS, and cortical subarachnoid hemorrhage (SAH). Three-dimensional black blood T1-weighted images using a motion-sensitized driven equilibrium three-dimensional turbo spin echo (MSDE) sequencing method revealed an intramural hematoma consistent with the extracranial vertebral artery. After 3 months, MSDE lost its abnormal signal. Our case was rare in that multiple phenomena of postpartum vascular disease occurred at the same time. In particular, we could reveal that this speculation was reversible in the MRI MSDE sequencing.
头痛是产后最常见的症状之一。其病因可能不明,也可能是以下疾病:颈内动脉夹层(CAD)、可逆性后部白质脑病综合征(PRES)和可逆性脑血管收缩综合征(RCVS)。有观点认为它们相互关联且机制相似,如小血管内皮功能障碍、自我调节缺陷以及后循环交感神经支配减少。然而,关于神经放射学表现的报道较少。我们遇到了一例罕见的产后同时发生多种血管疾病的病例。一名38岁女性产后突然出现霹雳样头痛。她神志清醒,无神经病变。计算机断层扫描显示蛛网膜下腔出血,包括额叶皮质表面。磁共振成像液体衰减反转恢复序列显示双侧基底节和右侧枕叶皮质有高强度区域。血管造影显示“串珠样”改变及左侧颅外椎动脉狭窄,但未发现动脉瘤。根据临床病程和神经放射学表现,我们将她诊断为产后血管疾病,包括CAD、PRES、RCVS和皮质下蛛网膜下腔出血(SAH)。使用运动敏感驱动平衡三维快速自旋回波(MSDE)序列方法的三维黑血T1加权图像显示与颅外椎动脉一致的壁内血肿。3个月后,MSDE序列的异常信号消失。我们的病例很罕见,因为产后血管疾病的多种现象同时出现。特别是,我们能够在MRI MSDE序列中发现这种推测是可逆的。