Ramya Sree Allavarapu, Sethumadhavan K, Pullakanam S P Tejaswi, Usharani Purimitla
Department of Microbiology, Aarupadai Veedu Medical College and Hospital, Vinayaka Mission's Research Foundation (VMRF-DU), Puducherry, Tamil Nadu, India.
Department of Biochemistry, Gayatri Vidya Parishad Institute of Health Care and Medical Technology, Marikavalasa, Visakhapatnam, Andhra Pradesh, India.
Bioinformation. 2024 Mar 31;20(3):223-228. doi: 10.6026/973206300200223. eCollection 2024.
The evaluation of infection rate for CoVid-19 cases among vaccinated and unvaccinated individuals using haematological parameters is of interest. Data such as age, gender, occupation, location, signs and symptoms, length of symptoms, date of sample collection and report generation, status of vaccinations, and outcome available in the database was used in this analysis. Ferritin levels, D-dimer values, CRP, troponin-1 levels and platelet count of each CoVid-19 patient were recorded and analysed. Data shows that maximum number of cases was reported during the second wave 143 (51.07%). The common age group affected was 31-40 years 28.56%. The common symptom identified was weakness in arms and legs among the unvaccinated group of CoVid-19 positive group. However, common symptom identified was fatigue (87%) among those who received only the first dose of CoVid vaccine. Nonetheless, the symptom identified was hair loss (68%) among those who received both the doses of CoVid vaccine. Thus, data shows that people do experience severe and life-threatening COVID-19 infection despite receiving the vaccination. Nonetheless, the infection is mild and very few individuals require hospitalization. No deaths are reported in the group that received the vaccination. This is in contrast to the unvaccinated group, which had a severe CoVid-19 infection with few deaths reported.
利用血液学参数评估接种疫苗和未接种疫苗个体中新冠病毒病例的感染率很有意义。本分析使用了数据库中诸如年龄、性别、职业、地点、体征和症状、症状持续时间、样本采集和报告生成日期、疫苗接种状况以及结果等数据。记录并分析了每位新冠患者的铁蛋白水平、D - 二聚体值、CRP、肌钙蛋白 - 1水平和血小板计数。数据显示，第二波报告的病例数最多，为143例（51.07%）。受影响的常见年龄组为31 - 40岁，占28.56%。在未接种疫苗的新冠阳性组中，确定的常见症状是手臂和腿部无力。然而，在仅接种了第一剂新冠疫苗的人群中，确定的常见症状是疲劳（87%）。尽管如此，在接种了两剂新冠疫苗的人群中，确定的症状是脱发（68%）。因此，数据表明，尽管接种了疫苗，人们仍会感染严重且危及生命的新冠病毒。尽管如此，感染症状较轻，很少有人需要住院治疗。接种疫苗的组中未报告死亡病例。这与未接种疫苗的组形成对比，该组出现了严重的新冠病毒感染，报告了少量死亡病例。
