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急性心肌梗死中唾液与血清高敏C反应蛋白的比较评估

Comparative Evaluation of Salivary and Serum High-Sensitive C-Reactive Protein in Acute Myocardial Infarction.

作者信息

SaranyaDevi K Sakthi, Rekha B Sasi, Thiyagarajan J Vijay, Dhivya R, Mihiran Suriyahanth, Santhosh S

机构信息

Department of Oral Medicine and Radiology, J.K.K. Nattraja Dental College and Hospitals, Namakkal, Tamil Nadu, India.

Department of Oral and Maxillofacial Surgery, J.K.K. Nattraja Dental College and Hospitals, Namakkal, Tamil Nadu, India.

出版信息

J Pharm Bioallied Sci. 2022 Jul;14(Suppl 1):S127-S130. doi: 10.4103/jpbs.jpbs_845_21. Epub 2022 Jul 13.

Abstract

AIM

The aim of this study is to comparatively evaluate the serum and salivary high-sensitive C-reactive protein (hs-CRP) in patients with acute myocardial infarction (MI).

SUBJECTS AND METHODS

The study group consisted of 60 patients of whom 30 were MI patients and 30 were controls. Serum hs-CRP was assessed using particle-enhanced immunoturbidimetric assay. Saliva hs-CRP is determined using a microplate reader cum UV photospectrometer from BMG.

RESULTS

In this study, levels of both serum and salivary hs-CRP in control and MI patients showed a positive correlation. Saliva can be used as an alternative biofluid to determine hs-CRP in MI patients.

CONCLUSION

Saliva can be used as a alternative biofluid to determine the risk as well as to determine prognosis in acute myocardial infarction.

摘要

目的

本研究旨在比较评估急性心肌梗死(MI)患者血清和唾液中的高敏C反应蛋白(hs-CRP)。

受试者与方法

研究组由60名患者组成,其中30例为MI患者,30例为对照组。采用颗粒增强免疫比浊法评估血清hs-CRP。使用BMG公司的酶标仪兼紫外分光光度计测定唾液hs-CRP。

结果

在本研究中,对照组和MI患者的血清和唾液hs-CRP水平均呈正相关。唾液可作为一种替代生物流体用于测定MI患者的hs-CRP。

结论

唾液可作为一种替代生物流体用于评估急性心肌梗死的风险以及判断预后。

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