Pituitary Center, Department of Neurosurgery, Seoul National University of College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Division of Pediatric Neurosurgery, Department of Neurosurgery, Seoul National University of College of Medicine, Seoul National University Children's Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Childs Nerv Syst. 2023 Sep;39(9):2367-2375. doi: 10.1007/s00381-022-05654-w. Epub 2022 Sep 16.
The pineal region is a challenging area for neurosurgeons due to its innate anatomical features, such as its deep location, surrounding large draining veins, and adjacent critical neural structures.
There is a high proportion of malignant tumors in the pineal gland, especially in children, and they are frequently accompanied by obstructive hydrocephalus. These cases require that surgical procedures can make a pathological diagnosis to guide further treatment strategies and immediately resolve increased intracranial pressure. Simultaneous endoscopic third ventriculostomy and biopsy have been regarded as the first-line surgical intervention before establishing a definite treatment plan. However, it is not always successful because various factors affect the surgical procedures, such as the location and extent of the tumor, degree of ventriculomegaly, location and size of the massa intermedia, and size of the foramen of Monro.
Here, we briefly reviewed the points to be considered in endoscopic biopsy of pineal tumors and introduced an alternative surgical procedure, the endoscopic endonasal trans-tuber cinereum approach, to surmount the anatomical hurdles.
由于松果体区域的固有解剖学特征,如位置深、周围有大的引流静脉以及毗邻的关键神经结构,因此该区域对神经外科医生来说是一个具有挑战性的领域。
松果体中恶性肿瘤的比例较高,尤其是在儿童中,且常伴有阻塞性脑积水。对于这些病例,手术过程需要进行病理诊断,以指导进一步的治疗策略,并立即解决颅内压增高的问题。在确定明确的治疗方案之前,同时进行内镜第三脑室造瘘术和活检被认为是一线手术干预措施。然而,由于各种因素会影响手术过程的成功率,如肿瘤的位置和范围、脑室扩张的程度、中间块的位置和大小,以及孟氏孔的大小等,因此并非总是如此。
在这里,我们简要回顾了在经内镜活检松果体肿瘤时需要考虑的要点,并介绍了一种替代的手术方法,即经内镜经鼻蝶入路,以克服解剖学障碍。