Dhermy P, Sterkers M, Morax S, Charlot J C, Savoldelli M
J Fr Ophtalmol. 1987;10(2):155-64.
The authors present four cases of Merkel cells tumor of the eyelid. These cases conform to the standard clinical and histological criteria specified in the dermatological literature. Immuno-histochemical studies have been performed (specific neuron enolase, cytokeratin KL 1). Il the last case an ultrastructural study has made evident the characteristic neurosecretory granulations and intermediate filaments. Various hypothesis concerning the origin of this tumor are discussed in light of anatomical evidence.
作者报告了4例眼睑默克尔细胞肿瘤。这些病例符合皮肤病学文献中规定的标准临床和组织学标准。已进行免疫组织化学研究(特异性神经元烯醇化酶、细胞角蛋白KL 1)。在最后一例中,超微结构研究显示出特征性的神经分泌颗粒和中间丝。根据解剖学证据讨论了关于该肿瘤起源的各种假说。