Madelain J, Turut P, Bego B, Beve C, Gonthier M F
Bull Soc Ophtalmol Fr. 1989 Feb;89(2):311-4.
We report one case of Merkel cell carcinoma. They commonly arise on the eyelids of elderly patients. Others localisations are on the skin of the pelvis. Clinical aspects, histological study, associating morphological aspect, ultra-structural and immuno-histo-chemical studies are characteristics enough to differentiate this tumor others tumors of the skin like cutaneous malignant lymphoma. The origin of this tumor is still discussed, but sure neuro-endocrinal. Possibility of visceral metastases on a small number of cases (6 to 8%) must be consider when treated. Total surgical ablation should be obtained.
我们报告1例默克尔细胞癌。该肿瘤常见于老年患者的眼睑,其他发病部位为盆腔皮肤。临床特征、组织学研究,结合形态学、超微结构和免疫组织化学研究,足以将该肿瘤与其他皮肤肿瘤如皮肤恶性淋巴瘤相鉴别。该肿瘤的起源仍存在争议,但肯定具有神经内分泌特性。治疗时必须考虑少数病例(6%至8%)发生内脏转移的可能性。应进行手术全切。