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Editorial: Future challenges and directions in determining allo-immunity in kidney transplantation.社论：肾移植中确定同种异体免疫的未来挑战与方向
Front Immunol. 2022 Aug 31;13:1013711. doi: 10.3389/fimmu.2022.1013711. eCollection 2022.
2
Epitope load identifies kidney transplant recipients at risk of allosensitization following minimization of immunosuppression.表位负荷可识别出在减少免疫抑制后发生同种异体致敏风险的肾移植受者。
Kidney Int. 2019 Jun;95(6):1471-1485. doi: 10.1016/j.kint.2018.12.029. Epub 2019 Mar 5.
3
Critical evaluation of a possible role of HLA epitope matching in kidney transplantation.对HLA表位匹配在肾移植中可能作用的批判性评估。
Transplant Rev (Orlando). 2020 Apr;34(2):100533. doi: 10.1016/j.trre.2020.100533. Epub 2020 Jan 17.
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Pre-transplant HLA Antibodies and Delayed Graft Function in the Current Era of Kidney Transplantation.移植前 HLA 抗体与当代肾移植中的延迟移植物功能。
Front Immunol. 2020 Aug 26;11:1886. doi: 10.3389/fimmu.2020.01886. eCollection 2020.
5
Humoral Immune Response and Allograft Function in Kidney Transplantation.体液免疫反应与肾移植中的同种异体移植物功能。
Am J Kidney Dis. 2015 Aug;66(2):337-47. doi: 10.1053/j.ajkd.2015.03.033. Epub 2015 May 16.
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HLA antibodies are associated with deterioration of kidney allograft function irrespective of donor specificity.HLA抗体与肾移植功能恶化相关，而与供体特异性无关。
Hum Immunol. 2021 Jan;82(1):19-24. doi: 10.1016/j.humimm.2020.10.010. Epub 2020 Nov 5.
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Non-HLA antibodies against endothelial targets bridging allo- and autoimmunity.针对同种异体和自身免疫的内皮细胞靶点的非 HLA 抗体。
Kidney Int. 2016 Aug;90(2):280-288. doi: 10.1016/j.kint.2016.03.019. Epub 2016 May 14.
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KIR and HLA-C interactions promote differential dendritic cell maturation and is a major determinant of graft failure following kidney transplantation.KIR 和 HLA-C 的相互作用促进了树突状细胞的成熟分化，是肾移植后移植物失功的主要决定因素。
PLoS One. 2011;6(8):e23631. doi: 10.1371/journal.pone.0023631. Epub 2011 Aug 31.
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Non-HLA-matched 3rd party vascular allograft in renal transplant may lead to sensitization against donor HLA.肾移植中使用非 HLA 匹配的第三方血管同种异体移植物可能会导致对供体 HLA 的致敏。
Clin Transplant. 2016 Nov;30(11):1508-1512. doi: 10.1111/ctr.12831. Epub 2016 Oct 7.
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Results of kidney transplantation in relation to HLA-A, B, DR matching and quality of donor organ.肾移植结果与HLA - A、B、DR配型及供体器官质量的关系
Proc Eur Dial Transplant Assoc. 1980;17:450-6.

引用本文的文献

1
Canadian Kidney Transplant Recipients', Transplant Candidates', and Caregivers' Perspectives on Precision Medicine and Molecular Matching in Kidney Allocation: A Qualitative Analysis.加拿大肾移植受者、移植候选人及护理人员对肾脏分配中精准医学和分子匹配的看法：一项定性分析
Can J Kidney Health Dis. 2025 May 23;12:20543581251342440. doi: 10.1177/20543581251342440. eCollection 2025.
2
Editorial: Emerging talents in alloimmunity and transplantation: 2022.社论：同种免疫与移植领域的新兴人才：2022年
Front Immunol. 2024 Mar 15;15:1393026. doi: 10.3389/fimmu.2024.1393026. eCollection 2024.
3
Canadian Kidney Transplant Professionals' Perspectives on Precision Medicine and Molecular Matching in Kidney Allocation.加拿大肾脏移植专业人士对肾脏分配中精准医学和分子匹配的看法。
Transplant Direct. 2023 Dec 18;10(1):e1565. doi: 10.1097/TXD.0000000000001565. eCollection 2024 Jan.

本文引用的文献

1
Early Post-Transplant Red Blood Cell Transfusion Is Associated With an Increased Risk of Transplant Failure: A Nationwide French Study.早期移植后红细胞输血与移植失败风险增加相关：一项全国性的法国研究。
Front Immunol. 2022 May 31;13:854850. doi: 10.3389/fimmu.2022.854850. eCollection 2022.
2
How to Ask the Right Question and Find the Right Answer: Clinical Research for Transplant Nephrologists.如何提出正确的问题并找到正确的答案：移植肾脏病学家的临床研究。
Front Immunol. 2022 May 10;13:879200. doi: 10.3389/fimmu.2022.879200. eCollection 2022.
3
Blood transfusion and the risk for infections in kidney transplant patients.肾移植患者的输血与感染风险
PLoS One. 2021 Nov 12;16(11):e0259270. doi: 10.1371/journal.pone.0259270. eCollection 2021.
4
On Path to Informing Hierarchy of Eplet Mismatches as Determinants of Kidney Transplant Loss.探寻将表位错配等级作为肾移植失败决定因素的依据。
Kidney Int Rep. 2021 Mar 30;6(6):1567-1579. doi: 10.1016/j.ekir.2021.03.877. eCollection 2021 Jun.
5
Early Posttransplant Blood Transfusion and Risk for Worse Graft Outcomes.移植后早期输血与移植结果较差的风险
Kidney Int Rep. 2021 Jan 16;6(4):986-994. doi: 10.1016/j.ekir.2020.12.038. eCollection 2021 Apr.
6
Eplet mismatch scores and de novo donor-specific antibody development in simultaneous pancreas-kidney transplantation.在胰肾联合移植中，Eplet 错配评分与新生供者特异性抗体的产生。
Hum Immunol. 2021 Mar;82(3):139-146. doi: 10.1016/j.humimm.2020.12.009. Epub 2020 Dec 31.
7
Analysis of T and B Cell Epitopes to Predict the Risk of Donor-Specific Antibody (DSA) Production After Kidney Transplantation: A Two-Center Retrospective Cohort Study.分析T细胞和B细胞表位以预测肾移植后供体特异性抗体（DSA）产生的风险：一项双中心回顾性队列研究。
Front Immunol. 2020 Aug 27;11:2000. doi: 10.3389/fimmu.2020.02000. eCollection 2020.
8
Death after Kidney Transplantation: An Analysis by Era and Time Post-Transplant.肾移植后的死亡：按时代和移植后时间分析。
J Am Soc Nephrol. 2020 Dec;31(12):2887-2899. doi: 10.1681/ASN.2020050566. Epub 2020 Sep 9.
9
Eplet Mismatch Load and Occurrence of Donor-Specific Anti-HLA Antibodies, Rejection, and Graft Failure after Kidney Transplantation: An Observational Cohort Study.Eplet 错配负荷与供体特异性抗 HLA 抗体、排斥反应和肾移植后移植物失败的发生：一项观察性队列研究。
J Am Soc Nephrol. 2020 Sep;31(9):2193-2204. doi: 10.1681/ASN.2020010019. Epub 2020 Aug 6.
10
Substituting imputation of HLA antigens for high-resolution HLA typing: Evaluation of a multiethnic population and implications for clinical decision making in transplantation.替代高分辨率 HLA 分型的 HLA 抗原推测：多民族人群的评估及其对移植中临床决策的影响。
Am J Transplant. 2021 Jan;21(1):344-352. doi: 10.1111/ajt.16070. Epub 2020 Jul 8.

Editorial: Future challenges and directions in determining allo-immunity in kidney transplantation.

作者信息

Lim Wai H, Ho Julie, Kosmoliaptsis Vasilis, Sapir-Pichhadze Ruth

机构信息

Department of Renal Medicine, Sir Charles Gairdner Hospital, Perth, WA, Australia.

Medical School, University of Western Australia, Perth, WA, Australia.

出版信息

Front Immunol. 2022 Aug 31;13:1013711. doi: 10.3389/fimmu.2022.1013711. eCollection 2022.

DOI:10.3389/fimmu.2022.1013711
PMID:36119031
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9473680/
Abstract
摘要