Beltagi Ahmed H El, Barakat Nour, Aker Loai, Abandeh Laith, Own Ahmed, Abdelhady Mohamed, Aboughalia Hassan
Neuroradiology Section, Neuroscience Institute, Hamad Medical Corporation, Weill Cornell Medicine, Doha, Qatar.
Ophthalmology Department, Hamad Medical Corporation, Doha, Qatar.
Radiol Case Rep. 2022 Sep 11;17(11):4264-4267. doi: 10.1016/j.radcr.2022.07.106. eCollection 2022 Nov.
We herein present a case of periventricular leukomalacia (PVL) with secondary optic pathway denervation atrophy, which was initially labeled as normal tension glaucoma. However, given the discordant clinical and ophthalmologic findings, brain magnetic resonance imaging was requested which proved PVL to be the underlying process to the patient's decreased visual acuity. In addition to presenting the ophthalmologic findings, we are emphasizing the pivotal role of neuroimaging in ruling out central causes of optic atrophy/hypoplasia and making this clinical distinction by demonstrating optic pathway atrophy associated with PVL.
我们在此报告一例伴有继发性视路去神经萎缩的脑室周围白质软化症(PVL),该病例最初被诊断为正常眼压性青光眼。然而,鉴于临床和眼科检查结果不一致,遂进行了脑部磁共振成像检查,结果证实PVL是导致患者视力下降的潜在病因。除了展示眼科检查结果外,我们还强调了神经影像学在排除视神经萎缩/发育不全的中枢性病因以及通过显示与PVL相关的视路萎缩来进行这种临床鉴别诊断中的关键作用。