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使用阿米妥钠(瓦达)技术对癫痫患者记忆功能的脑半球优势化研究

Lateralisation of memory functions in epileptic patients by use of the sodium amytal (Wada) technique.

作者信息

Powell G E, Polkey C E, Canavan A G

出版信息

J Neurol Neurosurg Psychiatry. 1987 Jun;50(6):665-72. doi: 10.1136/jnnp.50.6.665.

Abstract

Lateralisation of speech and memory functions was determined in 27 patients, being assessed for surgical treatment of unilateral temporal lobe epilepsy, using the sodium amytal procedure. The most common outcome with regard to language was the retention of normal left hemisphere dominance, regardless of handedness or side of lesion. In contrast, memory functions were most often to be found only in the unaffected hemisphere, also regardless of handedness or side of lesion. A lesion of either hemisphere appeared capable of interfering with language and verbal memory functions in an unexpectedly high proportion of patients.

摘要

对27例因单侧颞叶癫痫接受手术治疗评估的患者,采用阿米妥钠试验确定言语和记忆功能的偏侧化。关于语言,最常见的结果是保留正常的左半球优势,无论其利手情况或病灶侧别如何。相比之下,记忆功能最常仅在未受影响的半球中发现,同样与利手情况或病灶侧别无关。在出乎意料的高比例患者中,任一半球的病灶似乎都能够干扰语言和言语记忆功能。

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