Callegari C, Everett S, Ross M, Brasel J A
J Pediatr. 1987 Aug;111(2):240-3. doi: 10.1016/s0022-3476(87)80075-6.
To provide normative data, we measured anogenital distances in 115 infants of 25 to 42 weeks gestational age and 10 pregnant women, including anus to fourchette (AF), anus to base of the clitoris (AC), and fourchette to base of the clitoris (FC). All infant measurements showed positive and significant correlations with body surface area, weight, length, and gestational age (P less than 0.001). However, the anogenital ratio (AF/AC) followed a normal distribution and did not correlate with any of the anthropometric variables or age. Mean (+/- SD) value in infants was 0.37 +/- 0.07, and in adults, 0.36 +/- 0.07. An anogenital ratio greater than 0.50 falls outside the 95% confidence limits, suggests labioscrotal fusion, and indicates a need for further evaluation. Because it is independent of body size and gestational age, the anogenital ratio should be useful in diagnosing androgen-induced labioscrotal fusion in both premature and full-term female infants.
为提供规范数据，我们测量了115名孕龄为25至42周的婴儿及10名孕妇的肛殖距离，包括肛门至会阴（AF）、肛门至阴蒂根部（AC）以及会阴至阴蒂根部（FC）。所有婴儿测量值均与体表面积、体重、身长及孕龄呈显著正相关（P<0.001）。然而，肛殖比率（AF/AC）呈正态分布，且与任何人体测量变量或年龄均无相关性。婴儿的平均（±标准差）值为0.37±0.07，成人的为0.36±0.07。肛殖比率大于0.50超出95%置信区间，提示阴唇阴囊融合，表明需要进一步评估。由于肛殖比率独立于身体大小和孕龄，其在诊断早产和足月女婴雄激素诱导的阴唇阴囊融合方面应具有实用价值。
