Joseph Nitin, Suresh Sooraj, Prasad Satwiki, Malwee Swaraj Mandar, Brittas Anand, Gupta Vedant
Department of Community Medicine, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, India.
Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, India.
Egypt J Neurol Psychiatr Neurosurg. 2022;58(1):109. doi: 10.1186/s41983-022-00544-z. Epub 2022 Sep 15.
Restless leg syndrome (RLS) is a common neurological morbidity. It is, however, a frequently underdiagnosed medical condition. This study was hence done to assess the occurrence and severity of RLS among participants and to study its determinants and its association with quality of sleep. This was a cross-sectional study conducted among the general population of Mangalore in July 2021. Data were collected using a Google Form. The International Restless Legs Syndrome Study Group Rating Scale was used to diagnose RLS and its severity. The Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep quality.
The prevalence of RLS among the 202 participants was 24(11.9%). Among them, 5 were already diagnosed with RLS. Their mean age at onset was 40.4 ± 25.3 years. Among the rest 197 participants, 19(9.6%) were newly diagnosed with RLS. The severity of RLS was mild, moderate and severe among 7(36.8%), 9(47.4%) and 3(15.8%) participants, respectively. Five (26.3%) of the 19 newly diagnosed participants were identified as RLS sufferers. In multivariable analysis, the presence of diabetes mellitus and family history of RLS were associated with the presence of RLS among the participants. The mean Global PSQI value was 5.0 ± 3.1. Sleep latency was prolonged ( = 0.001), and sleep disturbances ( = 0.01) were higher among participants newly diagnosed with RLS ( = 19) compared to those without RLS ( = 178). Subjective sleep quality was poor ( = 0.038), and sleep disturbances ( = 0.016) were more among participants with severe degree RLS.
The prevalence of RLS in the present study was higher than that reported in previous Indian studies. Unpleasant sensations in RLS affected sleep initiation and maintenance among the affected. A multi-disciplinary approach is required to control its determinants and address other sleep-related problems among the RLS affected population.
不安腿综合征（RLS）是一种常见的神经疾病。然而，它是一种经常被漏诊的病症。因此，本研究旨在评估参与者中RLS的发生率和严重程度，并研究其决定因素及其与睡眠质量的关联。这是一项于2021年7月在芒格洛尔普通人群中进行的横断面研究。数据通过谷歌表单收集。使用国际不安腿综合征研究组评分量表来诊断RLS及其严重程度。匹兹堡睡眠质量指数（PSQI）用于评估睡眠质量。
202名参与者中RLS的患病率为24（11.9%）。其中，5人已被诊断为RLS。他们的平均发病年龄为40.4±25.3岁。在其余197名参与者中，19（9.6%）人新被诊断为RLS。RLS的严重程度在7（36.8%）、9（47.4%）和3（15.8%）名参与者中分别为轻度、中度和重度。19名新诊断参与者中有5（26.3%）人被确定为RLS患者。在多变量分析中，糖尿病的存在和RLS家族史与参与者中RLS的存在相关。PSQI总体平均值为5.0±3.1。与未患RLS的参与者（n = 178）相比，新诊断为RLS的参与者（n = 19）的睡眠潜伏期延长（P = 0.001），睡眠障碍（P = 0.01）更高。主观睡眠质量较差（P = 0.038），重度RLS参与者的睡眠障碍（P = 0.016）更多。
本研究中RLS的患病率高于先前印度研究报告的患病率。RLS中的不适感影响了患者的入睡和睡眠维持。需要采取多学科方法来控制其决定因素，并解决RLS患者群体中的其他睡眠相关问题。
