College of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou, 310018, China.
College of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou, 310018, China.
Chemosphere. 2022 Dec;308(Pt 3):136485. doi: 10.1016/j.chemosphere.2022.136485. Epub 2022 Sep 17.
In this study, the effects of polyamide (PA) microplastics on Drosophila were studied by analysing their effects on feeding, fecundity, metabolism and spontaneous activity, using Drosophila as a model organism. In the 0.1 g/L and 1 g/L groups, there was an increase in the amount of food consumed by female Drosophila melanogaster and a decrease in the amount of food consumed by males in both the 0.1 g/L and 20 g/L groups. In the TG assay, males showed a significant decrease in the 10 g/L and 20 g/L groups. The male group showed a significant decrease in protein content in the 10 g/L and 20 g/L groups. Glucose content decreased in the female Drosophila 1g/L and 10 g/L groups. The highest concentration group of 20 g/L showed a decrease in glucose content in male Drosophila. Only the male Drosophila in the highest concentration group showed increased daytime activity. Egg production by females decreased significantly after feeding microplastic food. The above assays demonstrate the potential effects of PA microplastics on flies, where the consumption of food containing microplastics leads to oxidative stress and inflammation, thus affecting the nutritional metabolism of flies.
本研究以果蝇为模型生物，通过分析聚酰胺（PA）微塑料对果蝇摄食、繁殖、代谢和自发活动的影响，研究 PA 微塑料对果蝇的影响。在 0.1g/L 和 1g/L 组中，雌性黑腹果蝇的摄食量增加，而在 0.1g/L 和 20g/L 组中雄性果蝇的摄食量减少。在 TG 检测中，10g/L 和 20g/L 组雄性的 TG 含量显著降低。10g/L 和 20g/L 组雄性的蛋白质含量显著降低。1g/L 和 10g/L 组雌性的葡萄糖含量降低。20g/L 最高浓度组雄性的葡萄糖含量降低。只有最高浓度组的雄性果蝇白天活动增加。食用含微塑料的食物后，雌性果蝇的产卵量显著减少。上述实验表明，PA 微塑料对果蝇有潜在影响，摄入含微塑料的食物会导致氧化应激和炎症，从而影响果蝇的营养代谢。
