Banivaheb Behrooz, Shahbazi Parmida, Hemmati Nima, Yahyavi Ashkan, Derakhshan Pegah, Tabatabaei Jabali Seyed Mohammad, Kabir Ali
Minimally Invasive Surgery Research Centre, Iran University of Medical Sciences, Tehran, Iran.
Research Center for Prevention of Cardiovascular Disease, Iran University of Medical Sciences, Tehran, Iran.
Med J Islam Repub Iran. 2022 May 7;36:46. doi: 10.47176/mjiri.36.46. eCollection 2022.
This study aims to provide information on the success rate of CPR in COVID-19 patients and some probable risk factors of mortality in these cases. In this historical cohort design, the CPR success rate probable risk factors of 737 critically ill patients during the COVID-19 pandemic in 17 hospitals in the catchment area of Iran University of Medical Sciences, Tehran, Iran, was evaluated between Feb and Apr 2020. Data were extracted from a database that is a part of a national integrated care electronic health record system and analyzed with logistic and Cox regression models. COVID-19 cases were 341 (46.3%). The mean age in COVID-19 cases and non-COVID-19 patients were 70.0±14.6 and 63.0±19.3 years, respectively (P<0.001). The mortality was significantly higher in COVID-19 patients (99.1% vs. 74%, OR: 39.6, 95%CI: 12.4, 126.2). Cardiovascular diseases were the most frequent underlying disease (46.3% of COVID-19 cases and 35.1% of non-COVID-19 patients). Being a COVID-19 case (OR: 29.0, 95%CI: 8.9, 93.2), Intensive care unit admission (OR: 2.6, 95%CI: 1.5, 4.6) and age for each ten-year increase (OR: 1.2, 95%CI: 1.1, 1.4) were observed to be independent risk factors of mortality following CPR. The hazard ratio of being a COVID-19 patient was HR= 1.8 (95%CI: 1.5, 2.1). Critically ill COVID-19 patients who undergo CPR have a decreased chance of survival in comparison to non-COVID-19 patients.
本研究旨在提供有关COVID-19患者心肺复苏成功率以及这些病例中一些可能的死亡风险因素的信息。在这项历史性队列研究设计中，于2020年2月至4月期间，对伊朗德黑兰医科大学集水区17家医院中737例在COVID-19大流行期间的重症患者的心肺复苏成功率及可能的风险因素进行了评估。数据从作为国家综合护理电子健康记录系统一部分的数据库中提取，并使用逻辑回归和Cox回归模型进行分析。COVID-19病例为341例（46.3%）。COVID-19病例和非COVID-19患者的平均年龄分别为70.0±14.6岁和63.0±19.3岁（P<0.001）。COVID-19患者的死亡率显著更高（99.1%对74%，OR：39.6，95%CI：12.4，126.2）。心血管疾病是最常见的基础疾病（COVID-19病例的46.3%和非COVID-19患者的35.1%）。确诊为COVID-19病例（OR：29.0，95%CI：8.9，93.2）、入住重症监护病房（OR：2.6，95%CI：1.5，4.6）以及年龄每增加十岁（OR：1.2，95%CI：1.1，1.4）被观察到是心肺复苏后死亡的独立风险因素。COVID-19患者的风险比为HR = 1.8（95%CI：1.5，2.1）。与非COVID-19患者相比，接受心肺复苏的重症COVID-19患者存活几率降低。
