State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, P. R. China.
Fujian Science & Technology Innovation Laboratory for Optoelectronic Information of China, Fuzhou, Fujian, 350108, P. R. China.
Adv Mater. 2022 Nov;34(44):e2201768. doi: 10.1002/adma.202201768. Epub 2022 Sep 30.
Metal-organic frameworks (MOFs) with well-defined porous structures and tailored functionalities have been widely used in chemical sensing. However, the integration of MOFs with flexible electronic devices for wearable sensing is challenging because of their low electrical conductivity and fragile mechanical properties. Herein, a wearable sweat sensor for metabolite detection is presented by integrating an electrically conductive Ni-MOF with a flexible nanocellulose substrate. The MOF-based layered film sensor with inherent conductivity, highly porous structure, and active catalytic properties enables the selective and accurate detection of vitamin C and uric acid. More importantly, the lightweight sensor can conformably self-adhere to sweaty skin and exhibits high water-vapor permeability. Furthermore, a wireless epidermal nutrition tracking system for the in situ monitoring of the dynamics of sweat vitamin C is demonstrated, the results of which are comparable to those tested by high-performance liquid chromatography. This study opens a new avenue for integrating MOFs as the active layer in wearable electronic devices and holds promise for the future development of high-performance electronics with enhanced sensing, energy production, and catalytic capabilities through the implementation of multifunctional MOFs.
具有明确多孔结构和定制功能的金属-有机骨架（MOFs）已被广泛应用于化学传感。然而，由于其导电性低和机械性能脆弱，将 MOFs 与柔性电子设备集成用于可穿戴传感具有挑战性。在此，通过将导电 Ni-MOF 与柔性纳米纤维素基底集成，提出了一种用于代谢物检测的可穿戴汗液传感器。基于 MOF 的分层膜传感器具有固有导电性、高多孔结构和活性催化特性，可实现对维生素 C 和尿酸的选择性和准确检测。更重要的是，这种重量轻的传感器可以贴合地自粘在出汗的皮肤上，并且具有高水蒸气透过率。此外，还展示了一种用于原位监测汗液中维生素 C 动力学的无线表皮营养跟踪系统，其结果与通过高效液相色谱测试的结果相当。这项研究为将 MOFs 集成作为可穿戴电子设备中的活性层开辟了新途径，并有望通过实施多功能 MOFs 来实现具有增强传感、能量产生和催化能力的高性能电子设备的未来发展。
