Indipendent researcher.
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Acta Biomed. 2022 Sep 22;93(S1):e2022271. doi: 10.23750/abm.v93iS1.13064.
International guidelines indicate pharmacological therapy and cognitive-behavioral therapy (CBT) as gold standard treatments for obsessive-compulsive disorder (OCD). However, up to 40% patients do not fully respond to CBT, thus manifesting persistent symptomatology. Empirical research reported brief strategic therapy (BST) as a potential treatment for OCD. The aim of the present study is to evaluate the efficacy of BST in treating OCD and to identify the clinical characteristics associated to response.
BST protocol was administered to patients with OCD. During a 24-weeks observational phase, the following scales have been administered at the baseline and every 4 weeks: Yale Brown Obsessive-Compulsive scale (Y-BOCS), Clinical Global Impression, Global Assessment of Functioning, Quality of Life Index, Medical Outcomes Study Short Form 12-item, Clinical Outcomes in Routine Evaluation-Outcome Measure, Generalized Anxiety Disorder Scale, Patient Health Questionnaire - 9 and Somatic Symptom Scale-8.
eight patients completed the treatment and a subgroup of five patients obtained clinical remission, defined as Y-BOCS total score < 25. The repeated measures ANOVA performed showed a significant decreased of the Y-BOCS total scores (p<.001). Comparisons between the two subgroups (remitters vs. non-remitters) highlighted some potential baseline characteristics associated with remission: i.e., higher mean level of anxiety, quality of life, physical health, and lower mean level of somatic symptoms and lower prevalence of personality disorders comorbidity.
BST could be a useful therapeutic strategy in treating OCD patients. Further studies with larger samples and with long-term follow-up are needed to assess the post-treatment maintenance of clinical effects.
国际指南表明,药物治疗和认知行为疗法(CBT)是强迫症(OCD)的金标准治疗方法。然而,多达 40%的患者对 CBT 没有完全反应,因此表现出持续的症状。实证研究报告了简短的策略治疗(BST)作为 OCD 的一种潜在治疗方法。本研究的目的是评估 BST 治疗 OCD 的疗效,并确定与反应相关的临床特征。
对 OCD 患者进行 BST 方案治疗。在 24 周的观察期内,在基线和每 4 周时,我们使用以下量表进行评估:耶鲁布朗强迫症量表(Y-BOCS)、临床总体印象、总体功能评估、生活质量指数、医疗结果研究短表 12 项、常规评估-结果测量中的临床结果、广泛性焦虑症量表、患者健康问卷-9 和躯体症状量表-8。
8 名患者完成了治疗,其中 5 名患者达到了临床缓解,定义为 Y-BOCS 总分<25。重复测量方差分析显示 Y-BOCS 总分显著降低(p<.001)。两组(缓解组与非缓解组)之间的比较突出了一些与缓解相关的潜在基线特征:即较高的平均焦虑、生活质量、身体健康水平,较低的躯体症状和人格障碍共病的平均水平。
BST 可能是治疗 OCD 患者的一种有用的治疗策略。需要进一步的研究,样本量更大,随访时间更长,以评估治疗后的临床效果的维持情况。