Department of Addiction Studies, School of Medical, Kashan University of Medical Sciences, Kashan, Iran.
Clinical Research Development Unit-Matini/Kargarnejad Hospital, Kashan University of Medical Sciences, Kashan, Iran.
Biol Trace Elem Res. 2023 Jul;201(7):3185-3192. doi: 10.1007/s12011-022-03422-0. Epub 2022 Sep 23.
Hookah smoking has been spreading around the world, especially among young adults. The current study aimed to investigate the concentration of heavy metals and elements and clinical symptoms in hookah users in comparison with non-users. To the best of our knowledge, the present study represents the first scientific contribution indicating levels of several heavy metals and elements in urine and blood in hookah users and non-users as well as evaluating clinical symptoms. This research was implemented in Iran among 100 males divided into two groups (50/group): control and hookah users. Heavy metal contamination (lead, cadmium, arsenic, thallium, zinc, and copper) in blood and urine samples was assayed by graphite furnace atomic absorption spectrometry (GFAAS). Duration of hookah use was 7.06 ± 4.57 years. The mean ± SD of lead, arsenic, and thallium concentrations was 3.77 ± 2.22, 8.50 ± 4.34, and 4.22 ± 2.69 μg/L. The mean levels of blood for lead, arsenic, and urinary thallium in hookah users are significantly higher than the control group (p < 0.05). The most frequent clinical symptoms in hookah smokers were constipation and fatigue. Findings from this study might guide the development of policies to regulate hookah smoking and prevent adverse health effects associated with hookah smoking.
水烟吸烟在全球范围内蔓延,尤其是在年轻人中。本研究旨在调查与非使用者相比,水烟使用者体内重金属和元素的浓度和临床症状。据我们所知,本研究首次科学地表明了水烟使用者和非使用者尿液和血液中的几种重金属和元素的水平,并评估了临床症状。这项研究在伊朗进行,共纳入 100 名男性,分为两组(每组 50 人):对照组和水烟使用者。通过石墨炉原子吸收光谱法(GFAAS)测定血液和尿液样本中的重金属污染(铅、镉、砷、铊、锌和铜)。水烟使用时间为 7.06±4.57 年。铅、砷和铊浓度的平均值±标准差分别为 3.77±2.22、8.50±4.34 和 4.22±2.69μg/L。水烟使用者血液中的铅、砷和尿铊的平均水平明显高于对照组(p<0.05)。水烟吸烟者最常见的临床症状是便秘和疲劳。本研究的结果可能为制定政策以规范水烟吸烟和预防与水烟吸烟相关的不良健康影响提供指导。