Department of Nursing, Joongbu University, Geumsan-gun 32713, Korea.
School of Nursing, Research Institute of Nursing Science, Hallym University, Chuncheon-si 24252, Korea.
Int J Environ Res Public Health. 2022 Sep 19;19(18):11832. doi: 10.3390/ijerph191811832.
This study investigated the effects of metabolic syndrome on the estimated glomerular filtration rate in middle-aged participants with diabetes to provide basic data to enable the development of education programs for middle-aged people to prevent diabetic kidney disease. This cross-sectional descriptive study analyzed data obtained in the 2nd year of the 8th Korea National Health and Nutrition Examination Survey in 2020 and enrolled 279 participants aged 40-65 years who were diagnosed with diabetes. Multilevel stratified cluster sampling was used to improve the representativeness of the samples and the accuracy of parameter estimation. The risk factors of metabolic syndrome and the risk of elevated eGFR were analyzed using regression analysis and the correlation between the variables was determined using Pearson's correlation analysis. Middle-aged participants with diabetes whose eGFR was <90 showed a significant difference in their risk for metabolic syndrome based on sex, age, disease duration, and total cholesterol concentrations. Systolic blood pressure and waist circumference in men, and waist circumference and HDL cholesterol level in women were identified as risk factors that contribute to the increasing prevalence of metabolic syndrome.
本研究旨在探讨代谢综合征对中年糖尿病患者估算肾小球滤过率的影响，为制定中年人群糖尿病肾病预防教育计划提供基础数据。这是一项横断面描述性研究，分析了 2020 年第八次韩国国家健康和营养调查的第 2 年的数据，共纳入了 279 名 40-65 岁被诊断为糖尿病的患者。采用多级分层聚类抽样方法，提高了样本的代表性和参数估计的准确性。使用回归分析对代谢综合征的危险因素和 eGFR 升高的风险进行了分析，并通过皮尔逊相关分析确定了变量之间的相关性。肾小球滤过率<90 的中年糖尿病患者，其代谢综合征的风险在性别、年龄、病程和总胆固醇浓度方面存在显著差异。男性的收缩压和腰围，以及女性的腰围和高密度脂蛋白胆固醇水平被确定为导致代谢综合征患病率增加的危险因素。
