Redd David S, Jensen Jamie L, Bodily Ruth J, Lee Abigail A, Skyles Ty J, Poole Brian D
Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.
Department of Biology, Brigham Young University, Provo, UT 84602, USA.
Vaccines (Basel). 2022 Aug 24;10(9):1382. doi: 10.3390/vaccines10091382.
Although most Human papillomavirus (HPV) infections are mild and are cleared by the immune system, some high-risk HPV strains can cause various cancers. Vaccines have been developed that protect against high-risk HPV strains. HPV vaccines have been approved for use by the CDC (Centers for Disease Control and Prevention) and are recommended for everyone aged 11-26. Despite the availability of safe and effective vaccines, uptake is low. HPV vaccine uptake has been extensively studied on a national and international level, but less is known about vaccine acceptance on a state or local level. The state of Utah, in the United States of America, has a relatively low HPV vaccination rate. In this study, we identified factors that impact the intent of Utah parents to vaccinate their children against HPV. A survey was distributed electronically to Utah residents. Survey results were analyzed using confirmatory factor analysis, structural equation modeling, and univariate analysis. Knowledge about HPV and positive vaccine attitudes had the greatest positive effect on intent to vaccinate children against HPV. Cautious sexual attitudes and high religious practice were found to have a negative impact on intent to vaccinate. Effective public health messaging will consider the cultural and religious influences of the target population.
虽然大多数人乳头瘤病毒（HPV）感染症状较轻，可被免疫系统清除，但一些高危型HPV毒株可引发各种癌症。目前已研发出预防高危型HPV毒株的疫苗。HPV疫苗已获美国疾病控制与预防中心（CDC）批准使用，建议11至26岁的所有人接种。尽管有安全有效的疫苗，但接种率较低。HPV疫苗接种情况在国家和国际层面已得到广泛研究，但在州或地方层面，人们对疫苗接受度的了解较少。美国犹他州的HPV疫苗接种率相对较低。在本研究中，我们确定了影响犹他州父母为子女接种HPV疫苗意愿的因素。通过电子方式向犹他州居民发放了调查问卷。使用验证性因素分析、结构方程模型和单变量分析对调查结果进行了分析。对HPV的了解和积极的疫苗态度对为儿童接种HPV疫苗的意愿产生了最大的积极影响。谨慎的性态度和高度的宗教活动被发现对接种意愿有负面影响。有效的公共卫生宣传将考虑目标人群的文化和宗教影响。
