AlMutairi Ghazi T
Department of Medicine, Unaizah College of Medicine and Medical Science, Qassim University, Saudi Arabia.
Ann Med Surg (Lond). 2022 Sep 2;81:104558. doi: 10.1016/j.amsu.2022.104558. eCollection 2022 Sep.
Antiepileptic drugs therapy are associated with myriad adverse effects. Some of antiepileptic drugs (AEDs) inhibit sodium channels that may cause dysrhythmia and hemodynamic instability if administered in too high dose.
We describe a patient with wide complex tachycardia likely secondary to medical management of status epilepticus specifically secondary to sodium channels blockade that successfully managed with supportive care and one session of hemodialysis.
In this case report, we discuss the successful management of the first reported combination of AEDs (Phenytoin and lacosamide) toxicity using supportive care and extracorporeal removal.
抗癫痫药物治疗会带来众多不良反应。一些抗癫痫药物（AEDs）会抑制钠通道，如果剂量过高，可能会导致心律失常和血流动力学不稳定。
我们描述了一名患有宽QRS波心动过速的患者，可能继发于癫痫持续状态的药物治疗，特别是继发于钠通道阻滞，通过支持治疗和一次血液透析成功治愈。
在本病例报告中，我们讨论了首例报道的AEDs（苯妥英和拉科酰胺）联合中毒，通过支持治疗和体外清除成功处理的情况。
