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一名儿童在出现中风后被诊断为中主动脉综合征和遗传性易栓症:病例报告。

A child diagnosed with midaortic syndrome and inherited thrombophilia after presenting with a stroke: A case report.

作者信息

Giacaman Narmeen, Tos Salem M, Ibdah Mohammad G, Ismail Mohamad K M, Ellahham Nael Hussein

机构信息

Al-Quds University, College of Medicine, Palestine.

Beit-Jala Governmental Hospital, Bethlehem, Palestine.

出版信息

Ann Med Surg (Lond). 2022 Aug 19;81:104455. doi: 10.1016/j.amsu.2022.104455. eCollection 2022 Sep.

DOI:10.1016/j.amsu.2022.104455
PMID:36147148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9486722/
Abstract

A 5-year-old female patient presented to the emergency room with right upper limb weakness, inability to speak and left side deviation of the mouth. Computed tomography (CT) scan was done and she was diagnosed with ischemic stroke. During her medical evaluation she was found to have high blood pressure (186/104 mm Hg). Investigations done to evaluate for secondary causes of hypertension and stroke revealed that she has inherited thrombophilia and abdominal aortic coarctation. Balloon angioplasty was done that lowered her elevated blood pressure, which was not responding well to antihypertensive medications, to near normal value for her age.

摘要

一名5岁女性患者因右上肢无力、无法言语及口角向左偏斜就诊于急诊室。进行了计算机断层扫描(CT),诊断为缺血性中风。在医学评估过程中,发现她患有高血压(186/104毫米汞柱)。为评估高血压和中风的继发原因所做的检查显示,她患有遗传性血栓形成倾向和腹主动脉缩窄。进行了球囊血管成形术,使她对降压药物反应不佳的高血压降至接近其年龄的正常水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cc4/9486722/42912aebf011/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cc4/9486722/bf75b55b77bb/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cc4/9486722/0ffc4dfde6d8/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cc4/9486722/42912aebf011/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cc4/9486722/bf75b55b77bb/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cc4/9486722/0ffc4dfde6d8/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cc4/9486722/42912aebf011/gr3.jpg

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本文引用的文献

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Midaortic syndrome in a middle-age female.中年女性的中段主动脉综合征。
BMJ Case Rep. 2021 Nov 9;14(11):e246530. doi: 10.1136/bcr-2021-246530.
2
The SCARE 2020 Guideline: Updating Consensus Surgical CAse REport (SCARE) Guidelines.SCARE 2020 指南:更新共识手术病例报告(SCARE)指南。
Int J Surg. 2020 Dec;84:226-230. doi: 10.1016/j.ijsu.2020.10.034. Epub 2020 Nov 9.
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Hypertension and childhood stroke.高血压与儿童脑卒中。
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Inherited Thrombophilia and the Risk of Arterial Ischemic Stroke: A Systematic Review and Meta-Analysis.遗传性血栓形成倾向与动脉缺血性脑卒中风险:系统评价和荟萃分析。
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Thrombophilia, risk factors and prevention.血栓形成倾向、危险因素和预防。
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Association of the A1298C polymorphism in MTHFR gene with ischemic stroke.亚甲基四氢叶酸还原酶(MTHFR)基因A1298C多态性与缺血性脑卒中的关联
J Clin Neurosci. 2014 Feb;21(2):198-202. doi: 10.1016/j.jocn.2013.04.017. Epub 2013 Oct 13.
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