Chen Wenlong, Chen Yaoyao, Xiao Ziwei, Zhang Yuhua, Zhang Tong, Zhong Guohua, Yi Xin
Key Laboratory of Crop Integrated Pest Management in South China, Ministry of Agriculture, South China Agricultural University, Guangzhou, China.
Key Laboratory of Natural Pesticide and Chemical Biology, Ministry of Education, South China Agricultural University, Guangzhou, China.
Front Physiol. 2022 Sep 6;13:1000547. doi: 10.3389/fphys.2022.1000547. eCollection 2022.
In insects, the emergence of mating behavior requires the interplay among sex-determination hierarchy mechanisms that regulate sex-specific differentiation, perception and integration of different sensory cues, and precisely patterned behavioral outputs. Biogenic amines, including octopamine (OA), dopamine (DA), tyramine (TA), serotonin and histamine, have been identified and proposed as putative neurotransmitters, neurohormones and/or neuromodulators in the central nervous system of insects to influence multiple physiologies and behaviors. The current study provides the physiological roles and pharmacology of these biogenic amines in the mating performance of . Silencing gene expressions coding for biosynthetic enzymes of DA and serotonin in male flies could decrease mating rates, while OA, TA and histamine had no such effects on mating. Furthermore, injection of DA or the DA receptor antagonist chlorpromazine could affect mating rate, as well as injection of serotonin. Pharmacological treatments with other biogenic amines or their receptor antagonists in male flies have no roles in regulating mating performance. We conclude that DA and its receptors are involved in regulating male mating behaviors in , while changes in serotonin levels in male flies could also affect mating rates. In the current study, the modulatory effects of these biogenic amines on mating performance were investigated, and these results will be helpful in providing a new strategy for controlling
在昆虫中，交配行为的出现需要性别决定层级机制之间的相互作用，这些机制调节性别特异性分化、不同感官线索的感知和整合以及精确模式化的行为输出。生物胺，包括章鱼胺（OA）、多巴胺（DA）、酪胺（TA）、5-羟色胺和组胺，已被鉴定并被认为是昆虫中枢神经系统中的假定神经递质、神经激素和/或神经调节剂，以影响多种生理和行为。当前的研究揭示了这些生物胺在[具体昆虫种类未提及]交配表现中的生理作用和药理学特性。在雄蝇中沉默编码DA和5-羟色胺生物合成酶的基因表达会降低交配率，而OA、TA和组胺对交配没有此类影响。此外，注射DA或DA受体拮抗剂氯丙嗪会影响交配率，注射5-羟色胺也会如此。用其他生物胺或其受体拮抗剂对雄蝇进行药理学处理在调节交配表现方面没有作用。我们得出结论，DA及其受体参与调节[具体昆虫种类未提及]中的雄性交配行为，而雄蝇中5-羟色胺水平的变化也会影响交配率。在当前研究中，研究了这些生物胺对交配表现的调节作用，这些结果将有助于为控制[具体控制对象未提及]提供新策略。
