Department of Community and Population Health, College of Health, Lehigh University, Bethlehem, Pennsylvania, United States of America.
Department of Biostatistics and Epidemiology, University of Massachusetts Amherst School of Public Health and Health Sciences, Amherst, Massachusetts, United States of America.
PLoS Comput Biol. 2022 Sep 23;18(9):e1010485. doi: 10.1371/journal.pcbi.1010485. eCollection 2022 Sep.
From February to May 2020, experts in the modeling of infectious disease provided quantitative predictions and estimates of trends in the emerging COVID-19 pandemic in a series of 13 surveys. Data on existing transmission patterns were sparse when the pandemic began, but experts synthesized information available to them to provide quantitative, judgment-based assessments of the current and future state of the pandemic. We aggregated expert predictions into a single "linear pool" by taking an equally weighted average of their probabilistic statements. At a time when few computational models made public estimates or predictions about the pandemic, expert judgment provided (a) falsifiable predictions of short- and long-term pandemic outcomes related to reported COVID-19 cases, hospitalizations, and deaths, (b) estimates of latent viral transmission, and (c) counterfactual assessments of pandemic trajectories under different scenarios. The linear pool approach of aggregating expert predictions provided more consistently accurate predictions than any individual expert, although the predictive accuracy of a linear pool rarely provided the most accurate prediction. This work highlights the importance that an expert linear pool could play in flexibly assessing a wide array of risks early in future emerging outbreaks, especially in settings where available data cannot yet support data-driven computational modeling.
从 2020 年 2 月至 5 月,传染病建模专家在 13 次调查中对新出现的 COVID-19 大流行的趋势提供了定量预测和估计。大流行开始时,现有传播模式的数据很少,但专家综合了他们掌握的信息,对大流行的现状和未来进行了定量的、基于判断的评估。我们通过对他们的概率陈述进行等权重平均,将专家预测汇总到一个单一的“线性汇总”中。在很少有计算模型对大流行做出公开估计或预测的时候,专家判断提供了(a)与报告的 COVID-19 病例、住院和死亡有关的短期和长期大流行结果的可证伪预测,(b)对潜在病毒传播的估计,以及(c)不同情景下大流行轨迹的反事实评估。尽管线性汇总方法的预测准确性很少提供最准确的预测,但它比任何单个专家的预测都更准确。这项工作强调了专家线性汇总在灵活评估未来新发疫情中广泛风险方面的重要性,尤其是在现有数据尚不能支持数据驱动的计算建模的情况下。