Natroshvili Tinatin, Peperkamp Kirsten, Malyar Masoud A, Wijnberg David, Heine Erwin P, Walbeehm Erik T
Department of Plastic and Reconstructive Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
Department of Plastic and Reconstructive Surgery, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
Arch Plast Surg. 2022 Sep 23;49(5):656-662. doi: 10.1055/s-0042-1756345. eCollection 2022 Sep.
The median nerve can be compressed due to a tumor along the course of the median nerve, causing typical compression symptoms or even persistence or recurrence after an operation. The aim of this review is to provide a comprehensive overview of rare tumors described in recent publications that cause median nerve compression and to evaluate treatment options. The PubMed, Embase, and Web of Science databases were searched for studies describing median nerve compression due to a tumor in adults, published from the year 2000 and written in English. From 94 studies, information of approximately 100 patients have been obtained. The rare tumors causing compression were in 32 patients located at the carpal tunnel, in 21 cases in the palm of the hand, and 28 proximal from the carpal tunnel. In the other cases the compression site extended over a longer trajectory. There were 37 different histological types of lesions. Complete resection of the tumor was possible in 58 cases. A total of 8 patients presented for the second time after receiving initial therapy. During follow-up, three cases of recurrence were reported with a mean follow-up period of 11 months. The most common published cause of median nerve compression is the lipofibromatous hamartoma. Besides the typical sensory and motor symptoms of median nerve compression, a thorough physical examination of the complete upper extremity is necessary to find any swelling or triggering that might raise suspicion of the presence of a tumor.
正中神经可能会因沿其走行的肿瘤而受压，导致典型的压迫症状，甚至在手术后持续存在或复发。本综述的目的是全面概述近期出版物中描述的导致正中神经受压的罕见肿瘤，并评估治疗方案。在PubMed、Embase和科学网数据库中检索了2000年以来发表的、用英文撰写的关于成人肿瘤导致正中神经受压的研究。从94项研究中，获得了约100名患者的信息。导致压迫的罕见肿瘤在32例位于腕管，21例位于手掌，28例位于腕管近端。在其他病例中，压迫部位延伸至更长的轨迹。共有37种不同的组织学类型病变。58例患者可行肿瘤完整切除。共有8例患者在接受初始治疗后再次就诊。随访期间，报告了3例复发，平均随访期为11个月。已发表的正中神经受压最常见原因是脂肪纤维瘤性错构瘤。除了正中神经受压的典型感觉和运动症状外，对整个上肢进行全面体格检查对于发现任何可能引起肿瘤怀疑的肿胀或触发点很有必要。
