Almusarhed Manar, Eldeeb Hany
Department of Oncology, Milton Keynes Hospital NHS Foundation Trust, Milton Keynes, UK.
Department of Oncology, University of Buckingham, Buckingham, UK.
BMJ Case Rep. 2017 Aug 20;2017:bcr-2017-220597. doi: 10.1136/bcr-2017-220597.
Although direct muscle invasion by carcinoma is well recognised, skeletal muscle metastases are rare. Breast cancer very rarely metastasises to skeletal muscles. We present a case of breast cancer that metastasised to the biceps muscle. The woman developed breast cancer in 1990 and then developed axillary subcutaneous metastasis in 2001. In 2015, she presented with pain in the left forearm extending to the hand. Initial imaging showed no abnormalities, but the positron emission tomography-CT scanning revealed a hot spot in the left biceps muscle. Additionally, the nerve conduction study showed feature of carpal tunnel syndrome. The hot spot was deemed inconclusive in the view of normal CT and MRI scans, and the patient was treated with carpal tunnel decompression. A few months later, the patient developed a lump in the left biceps muscle, which appeared to be a metastatic lesion from her primary breast cancer. The patient was treated with radiotherapy and responded satisfactorily.
尽管癌直接侵犯肌肉已广为人知,但骨骼肌转移却很罕见。乳腺癌极少转移至骨骼肌。我们报告一例乳腺癌转移至肱二头肌的病例。该女性于1990年患乳腺癌,2001年出现腋窝皮下转移。2015年,她出现左前臂至手部疼痛。初始影像学检查未发现异常,但正电子发射断层扫描-CT显示左肱二头肌有一个热点。此外,神经传导研究显示有腕管综合征的特征。鉴于CT和MRI扫描正常,该热点被认为不能确诊,患者接受了腕管减压治疗。几个月后,患者左肱二头肌出现肿块,似乎是原发性乳腺癌的转移灶。患者接受了放疗,反应良好。