Leung Cindy W, Heisler Michele, Patel Minal R
Department of Nutritional Sciences, School of Public Health, University of Michigan, Ann Arbor, United States.
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, United States.
Prev Med Rep. 2022 Aug 19;29:101957. doi: 10.1016/j.pmedr.2022.101957. eCollection 2022 Oct.
Adults from structurally marginalized populations have disproportionately higher rates of diabetes, highlighting the importance of addressing social risk factors in diabetes prevention and management. This study examined the correlations among multiple social risk factors and their respective burden on diabetes management and psychosocial health outcomes among adults with diabetes. Data came from the baseline assessment of an ongoing randomized controlled trial evaluating approaches to addressing unmet social needs among 579 adults with diabetes Four social risks (food insecurity, financial insecurity, housing insecurity, and utility insecurity) were assessed, dichotomized and summed to create a score of cumulative social risk factors. The outcomes of interest were: hemoglobin A1c, cost-related non-adherence for diabetes, diabetes distress, and anxiety or depression. Multivariate regression models were used to examine the associations between cumulative social risk factors and health outcomes, adjusting for sociodemographic characteristics and diabetes duration. Approximately 18% of study participants reported one social risk, 18% reported two social risks, and 23% reported three or four social risks. After multivariate adjustment, adults with three or four social risk factors had a greater likelihood of cost-related non-adherence (OR 2.81, 95% CI 1.95, 4.06), diabetes distress (OR 3.03, 95% CI 2.13, 4.31), and anxiety or depression (OR 5.36, 95% CI 3.39, 8.47), compared to adults with no social risk factors. Significant dose-response relationships were observed with greater social risk factors and poorer diabetes-related outcomes. These findings support efforts to address systemic contributors to diabetes management and care to better promote individual and population health.
来自结构上处于边缘地位人群的成年人患糖尿病的比例异常偏高,这凸显了在糖尿病预防和管理中解决社会风险因素的重要性。本研究调查了多种社会风险因素之间的相关性,以及它们对糖尿病成年患者的糖尿病管理和心理社会健康结果各自造成的负担。数据来自一项正在进行的随机对照试验的基线评估,该试验评估了满足579名糖尿病成年患者未满足的社会需求的方法。评估了四种社会风险(粮食不安全、财务不安全、住房不安全和水电供应不安全),将其进行二分法处理并求和,以得出累积社会风险因素得分。感兴趣的结果包括:糖化血红蛋白、糖尿病相关费用导致的治疗依从性不佳、糖尿病困扰以及焦虑或抑郁。使用多变量回归模型来研究累积社会风险因素与健康结果之间的关联,并对社会人口统计学特征和糖尿病病程进行了调整。约18%的研究参与者报告有一种社会风险,18%报告有两种社会风险,23%报告有三种或四种社会风险。经过多变量调整后,与没有社会风险因素的成年人相比,有三种或四种社会风险因素的成年人因费用导致治疗依从性不佳的可能性更大(比值比2.81,95%置信区间1.95,4.06)、糖尿病困扰的可能性更大(比值比3.03,95%置信区间2.13,4.31)以及焦虑或抑郁的可能性更大(比值比5.36,95%置信区间3.39,8.47)。观察到社会风险因素越多与糖尿病相关结果越差之间存在显著的剂量反应关系。这些发现支持了为解决糖尿病管理和护理的系统性因素以更好地促进个体和人群健康所做的努力。