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睡眠与自闭症:当前研究、临床评估及治疗策略

Sleep and Autism: Current Research, Clinical Assessment, and Treatment Strategies.

作者信息

Estes Annette, Hillman Arianna, Chen Maida Lynn

机构信息

Department of Speech and Hearing Sciences (Estes) and Department of Pediatrics, Division of Pulmonary and Sleep Medicine (Chen), University of Washington, Seattle; University of Washington Autism Center (Estes, Hillman); Pediatric Sleep Disorders Center and Pulmonary and Sleep Medicine Division, Seattle Children's Hospital (Chen).

出版信息

Focus (Am Psychiatr Publ). 2024 Apr;22(2):162-169. doi: 10.1176/appi.focus.20230028. Epub 2024 Apr 10.

DOI:10.1176/appi.focus.20230028
PMID:38680972
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11046719/
Abstract

Autism spectrum disorder is associated with a high rate of sleep problems, affecting over 80% of autistic individuals. Sleep problems have pervasive negative effects on health, behavior, mood, and cognition but are underrecognized in autistic children. Problems initiating and maintaining sleep-hallmarks of insomnia-are common. Sleep-disordered breathing and restless legs syndrome have also been described in autism at a higher prevalence than in community populations. The authors describe current research on sleep in autistic children and potential pathophysiologic mechanisms. They describe practical approaches to sleep assessment and synthesize approaches to addressing sleep problems in autistic children.

摘要

自闭症谱系障碍与高比例的睡眠问题相关,超过80%的自闭症患者受其影响。睡眠问题对健康、行为、情绪和认知有着普遍的负面影响,但在自闭症儿童中却未得到充分认识。入睡困难和维持睡眠困难——失眠的典型特征——很常见。睡眠呼吸障碍和不宁腿综合征在自闭症患者中的患病率也高于普通人群。作者描述了目前关于自闭症儿童睡眠的研究以及潜在的病理生理机制。他们介绍了睡眠评估的实用方法,并综合了应对自闭症儿童睡眠问题的方法。

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Neurobiol Sleep Circadian Rhythms. 2023 May 22;14:100096. doi: 10.1016/j.nbscr.2023.100096. eCollection 2023 May.
2
Sleep disturbances in autism spectrum disorder: Animal models, neural mechanisms, and therapeutics.自闭症谱系障碍中的睡眠障碍:动物模型、神经机制及治疗方法
Neurobiol Sleep Circadian Rhythms. 2023 Apr 26;14:100095. doi: 10.1016/j.nbscr.2023.100095. eCollection 2023 May.
3
Control of Breathing and Central Hypoventilation Syndromes.呼吸控制与中枢性通气不足综合征
Sleep Med Clin. 2023 Jun;18(2):161-171. doi: 10.1016/j.jsmc.2023.01.002.
4
Co-occurring conditions in children with Down syndrome and autism: a retrospective study.唐氏综合征与自闭症共病儿童的共存病症:一项回顾性研究。
J Neurodev Disord. 2023 Mar 2;15(1):9. doi: 10.1186/s11689-023-09478-w.
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Sleep Disorders in Children with Prader Willi Syndrome: Current Perspectives.普拉德-威利综合征患儿的睡眠障碍:当前观点
Nat Sci Sleep. 2022 Nov 10;14:2065-2074. doi: 10.2147/NSS.S361518. eCollection 2022.
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