Kamran Ateeba, Salman Maira, Siddiqui Rida, Shabbir Noor Zehra, Rohail Samia, Sukaina Mahnoor
Karachi Medical and Dental College, Karachi, Pakistan.
Ann Med Surg (Lond). 2022 Oct;82:104773. doi: 10.1016/j.amsu.2022.104773. Epub 2022 Sep 22.
The re-emergence of polio in the UK reminds us that the global threat of polio remains. Viruses know no bounds or borders. COVID-19, Monkeypox, and polio are evidence of this. Poliomyelitis was once the leading cause of death and paralysis in the UK and globally. With the introduction of vaccines during the 1950s-1960s, polio was eradicated from most developed countries, including the UK. The last case of wild polio was in 1984, and the UK was polio-free in 2003. The recent detection of vaccine-derived poliovirus type 2 in London sewage samples is alarming. Routine inoculations were adversely affected due to COVID-19, and UK's wastewater monitoring program was suspended due to economic restrictions. The UK faces several challenges with the burden of COVID-19, Monkeypox, and the return of polio could further burden the already pandemic-stricken healthcare system. To prevent further epidemics in the UK, wastewater sampling remains crucial in evaluating, searching, and eradicating the spread of poliovirus. Further epidemiological surveillance in adjacent areas to the Beckton plant is crucial to filling any gaps in understanding the outbreak's extent and guiding the initiation of appropriate and timely public health measures. The importance of vaccination in unvaccinated or incompletely vaccinated individuals cannot be overstated, especially in areas where vaccination rates are low. The risk of polio remains globally until its complete eradication from endemic countries. Until elimination, a global effort should be made to minimize the risk and the consequent spread of poliovirus by maintaining strong population immunity levels through high vaccination coverage.
脊髓灰质炎在英国的再度出现提醒我们,脊髓灰质炎的全球威胁依然存在。病毒没有界限或国界。新冠病毒、猴痘病毒和脊髓灰质炎病毒就是例证。脊髓灰质炎曾是英国乃至全球死亡和瘫痪的主要原因。随着20世纪50年代至60年代疫苗的引入,包括英国在内的大多数发达国家已根除脊髓灰质炎。最后一例野生脊髓灰质炎病例出现在1984年,英国于2003年实现无脊髓灰质炎状态。最近在伦敦污水样本中检测到2型疫苗衍生脊髓灰质炎病毒令人担忧。常规接种因新冠疫情受到不利影响,英国的废水监测项目也因经济限制而暂停。英国在应对新冠疫情、猴痘疫情方面面临诸多挑战,而脊髓灰质炎的再度出现可能会给本就饱受疫情冲击的医疗系统带来更大负担。为防止英国出现更多疫情,废水采样对于评估、搜寻和根除脊髓灰质炎病毒的传播仍然至关重要。对贝克顿工厂周边地区进行进一步的流行病学监测,对于填补在了解疫情范围方面的任何空白以及指导及时启动适当的公共卫生措施至关重要。对于未接种或未完全接种疫苗的人群,接种疫苗的重要性再怎么强调也不为过,尤其是在疫苗接种率较低的地区。在脊髓灰质炎在流行国家被彻底根除之前,全球范围内脊髓灰质炎风险依然存在。在实现根除之前,应通过全球共同努力,通过高疫苗接种覆盖率维持强大的人群免疫水平,以尽量降低脊髓灰质炎病毒的风险及其后续传播。