儿童腺病毒 7 型感染致病毒性败血症和脑炎致死 1 例
A fatal case of viral sepsis and encephalitis in a child caused by human adenovirus type 7 infection.
机构信息
Beijing Key Laboratory of Pediatric Respiratory Infection Diseases, Key Laboratory of Major Diseases in Children, Ministry of Education, National Clinical Research Center for Respiratory Diseases, National Key Discipline of Pediatrics (Capital Medical University), National Center for Children's Health, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Research Unit of Critical Infection in Children, Chinese Academy of Medical Sciences, 2019RU016, Beijing, China.
出版信息
Virol J. 2022 Sep 28;19(1):154. doi: 10.1186/s12985-022-01886-z.
Adenoviruses are highly prevalent pathogens responsible for a wide range of clinical diseases, including respiratory tract infection, acute gastroenteritis, and conjunctivitis. However, adenovirus infection is rarely associated with central nervous system involvement. Here, we report a fatal viral sepsis and encephalitis in a child caused by a human adenovirus type 7 infection. We detected human adenovirus type 7 in the patient's nasopharyngeal swab, blood, and cerebrospinal fluid. Our findings indicate clinicians should be aware of the possible central nervous system involvement in adenovirus infection.
腺病毒是一种高度流行的病原体，可导致多种临床疾病，包括呼吸道感染、急性胃肠炎和结膜炎。然而，腺病毒感染很少与中枢神经系统受累有关。在这里，我们报告了一例由人类腺病毒 7 型感染引起的儿童致命性病毒败血症和脑炎。我们在患者的鼻咽拭子、血液和脑脊液中检测到了人类腺病毒 7 型。我们的研究结果表明，临床医生应该意识到腺病毒感染可能涉及中枢神经系统。
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