新冠病毒感染所致心肌炎与信使核糖核酸疫苗相关心包炎：一例报告

Voltarelli Clara L, Silva Luiza, Longo Mariana, Ferraria Stefany, Martins Lucas L, Nazar Guilherme, Magalhães Tiago, Miyazima Rafael, Lenci Marques Gustavo

Internal Medicine Department, Federal University of Parana, Curitiba, BRA.

Radiology Department, Federal University of Parana, Curitiba, BRA.

Cureus. 2022 Aug 26;14(8):e28440. doi: 10.7759/cureus.28440. eCollection 2022 Aug.

Acute inflammatory cardiac disease is an increasing cause of COVID-19 vaccine-induced complications. We report a case of acute pericarditis following the second dose of the COVID-19 vaccine (BNT162b2) in a 49-year-old woman with previous COVID-19-induced myocarditis and heart failure. A clinical presentation compatible with acute decompensated heart failure elevated troponin levels and a cardiac-MRI showing myocardial fibrosis and inflammatory pericardial effusion led to the diagnosis of perimyocarditis. She was treated with non-steroidal anti-inflammatory drugs (NSAIDs) and colchicine. Her condition improved in eight days. Physicians should be aware of the possible diagnosis of pericarditis and/or a myocardial injury after COVID-19 infection and vaccination.

急性炎症性心脏病是新冠疫苗诱导并发症的一个日益常见的病因。我们报告了一例49岁女性在接种第二剂新冠疫苗（BNT162b2）后发生急性心包炎的病例，该女性既往有新冠病毒感染诱发的心肌炎和心力衰竭病史。临床表现符合急性失代偿性心力衰竭，肌钙蛋白水平升高，心脏磁共振成像显示心肌纤维化和炎性心包积液，从而诊断为心肌心包炎。她接受了非甾体抗炎药（NSAIDs）和秋水仙碱治疗。八天后病情好转。医生应意识到新冠病毒感染和接种疫苗后可能诊断为心包炎和/或心肌损伤。