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高剂量静脉注射维生素C治疗寨卡热

High Dose Intravenous Vitamin C Treatment for Zika Fever.

作者信息

Gonzalez Michael J, Berdiel Miguel J, Miranda-Massari Jorgé R, Duconge Jorgé, Rodríguez-López Joshua L, Adrover-López Pedro A

机构信息

University of Puerto Rico, Medical Sciences Campus, Schools of Public Health and Pharmacy, San Juan, PR, 00936-5067.

Berdiel Clinic, Ponce, PR, 00716.

出版信息

J Orthomol Med. 2016;31(1):19-22.

Abstract

The Zika Fever is a viral disease caused by a single-stranded RNA virus from the Flavivirus genus, Flaviviridae family, from the Spondweni group. Its transmission occurs through mosquito vectors, principally Aedes Aegypti. The most common symptoms of Zika are fever, rash, joint pain, and conjunctivitis (red eyes). Other common symptoms include muscle pain and headache. As of now, no vaccine exists for the virus and no official treatment has been developed aside from standard procedures of the use of acetaminophen (paracetamol) and non-steroidal anti-inflammatory drugs. This is a case report of a 54 year-old Hispanic female who arrived at the clinic with symptomatology congruent with the Zika fever. The patient was treated with high doses of intravenous vitamin C over three days. The symptoms resolved after the infusions without any side effects at day four. Recovery from this viral infection takes normally around two weeks. Based on the positive outcome in this case, we propose that intravenous vitamin C should be studied further as a potential treatment for acute viral infections.

摘要

寨卡热是一种由黄病毒科黄病毒属Spondweni组的单链RNA病毒引起的病毒性疾病。它通过蚊媒传播,主要是埃及伊蚊。寨卡热最常见的症状是发热、皮疹、关节疼痛和结膜炎(红眼)。其他常见症状包括肌肉疼痛和头痛。截至目前,尚无针对该病毒的疫苗,除了使用对乙酰氨基酚(扑热息痛)和非甾体抗炎药的标准程序外,尚未开发出官方治疗方法。这是一份病例报告,一名54岁的西班牙裔女性因出现与寨卡热相符的症状前来诊所就诊。该患者接受了为期三天的大剂量静脉注射维生素C治疗。输液后症状在第四天消失,没有任何副作用。这种病毒感染通常需要大约两周才能康复。基于该病例的积极结果,我们建议进一步研究静脉注射维生素C作为急性病毒感染的潜在治疗方法。

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