Deccan Multispeciality Hardikar Hospital, Pune, Maharashtra, India.
School of Health Sciences, Toros University, Mersin, Turkey.
Dermatol Ther. 2022 Nov;35(11):e15876. doi: 10.1111/dth.15876. Epub 2022 Oct 9.
Food and Drug Administration approved indications of hyaluronic acid fillers include some facial wrinkles or skin folds like naso-labial folds, perioral wrinkles, volumization of lip, cheek, chin, and dorsal region of the hands, also acne scars and lipoatrophy of human immunodeficiency virus positive patients. This article reviews the off-label indications of hyaluronic acid fillers such as connective tissue disorders (lupus erythematosus, scleroderma, and dermatomyositis), lipoatrophy associated with other diseases, breast volumization, giving volume to buttocks and the feet, implant into bone, tendon, ligament or muscle, injection to glabella, nose, periorbital region, forehead, or neck.
美国食品和药物管理局批准的透明质酸填充剂的适应证包括一些面部皱纹或皮肤褶皱，如鼻唇沟、口周皱纹、唇部、脸颊、下巴和手部背部的体积增大，以及痤疮疤痕和人类免疫缺陷病毒阳性患者的脂肪萎缩。本文综述了透明质酸填充剂的超适应证，如结缔组织疾病（红斑狼疮、硬皮病和皮肌炎）、与其他疾病相关的脂肪萎缩、乳房增大、臀部和足部增大、植入骨、肌腱、韧带或肌肉、眉间、鼻子、眶周区域、额头或颈部注射。
