Wang Hao, Chen Lingli, Cao Yuan, Xie Kaixu, Wang Chunmei, Pei Pei, Guo Yu, Bragg Fiona, Yu Min, Chen Zhengming, Li Liming
Department of NCDs Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, #3399 Binsheng road, Binjiang District, Hangzhou, Zhejiang Province, China.
Department of NCDs Control and Prevention, Tongxiang City Center for Disease Control and Prevention, Tongxiang, China.
Nutr Metab (Lond). 2022 Sep 30;19(1):67. doi: 10.1186/s12986-022-00703-2.
Hypertension, a well-known risk factor, contributes to millions of deaths from cardiovascular and renal diseases worldwide. However, evidence on the association between frequency of dairy product consumption and hypertension is inconsistent.
The data for the present study are from the Tongxiang baseline dataset of the China Kadoorie Biobank prospective study. A total of 53,916 participants aged 30-79 years were included in the final analysis. Multivariable logistic regression was utilized to evaluate the association of dairy product consumption with hypertension, and multiple linear regression was conducted to assess the association of dairy product consumption with systolic and diastolic blood pressure.
Of the 53,916 participants, 2.6% reported consuming dairy products weekly, and 44.4% had prevalent hypertension. After adjusting for socio-demographic status, lifestyle factors, BMI, waist circumference, sleep duration and snoring, when compared with participants who never consumed dairy products, the odds ratios (95% CI) for hypertension among those consuming dairy products less than once per week, and ≥ 1 time per week were 0.85 (0.77-0.95) and 0.74 (0.65-0.84), respectively. The corresponding odds ratios (95% CI) for men were 0.85 (0.71-1.02) and 0.75 (0.61-0.92), respectively (P = 0.001), and for women were 0.88 (0.76-1.01) and 0.77 (0.65-0.91), respectively. (P < 0.001).
In this large epidemiological study, higher frequency of dairy product consumption is associated with significantly lower odds of hypertension among Chinese adults.
高血压是一种众所周知的风险因素，在全球范围内导致数百万例心血管和肾脏疾病死亡。然而，关于乳制品消费频率与高血压之间关联的证据并不一致。
本研究的数据来自中国嘉道理生物银行前瞻性研究的桐乡基线数据集。最终分析纳入了53916名年龄在30 - 79岁的参与者。采用多变量逻辑回归评估乳制品消费与高血压的关联，并进行多元线性回归以评估乳制品消费与收缩压和舒张压的关联。
在53916名参与者中，2.6%的人报告每周食用乳制品，44.4%的人患有高血压。在调整了社会人口统计学状况、生活方式因素、体重指数、腰围、睡眠时间和打鼾情况后，与从未食用乳制品的参与者相比，每周食用乳制品少于一次和每周≥1次的参与者患高血压的比值比（95%置信区间）分别为0.85（0.77 - 0.95）和0.74（0.65 - 0.84）。男性的相应比值比（95%置信区间）分别为0.85（0.71 - 1.02）和0.75（0.61 - 0.92）（P = 0.001），女性分别为0.88（0.76 - 1.01）和0.77（0.65 - 0.91）（P < 0.001）。
在这项大型流行病学研究中，中国成年人中较高的乳制品消费频率与显著较低的高血压患病几率相关。
