Department of Occupational Health Engineering, School of Health, Kashan University of Medical Sciences, Kashan, Iran.
School of Public Health, College of Public Health, Taipei Medical University, Taipei, Taiwan.
Environ Sci Pollut Res Int. 2023 Feb;30(6):16386-16397. doi: 10.1007/s11356-022-23353-6. Epub 2022 Oct 1.
Formaldehyde is categorized as a definitive carcinogen by the International Agency for Research on Cancer. To the best of our knowledge, no study has assessed the health risks of occupational exposure of workers in carpet manufacturing plants to formaldehyde. Therefore, this study assesses the health risks of the occupational exposure to formaldehyde of 67 male workers in carpet manufacturing plants in Iran in 2022. Exposure to formaldehyde was quantitatively determined after collecting personal exposure samples from the workers' respiratory zone and spectrophotometric analysis based on method number 3500 of the National Institute of Occupational Safety and Health. In the next step, the carcinogenic and noncarcinogenic risks based on personal exposure to formaldehyde were evaluated. Sensitivity analyses were employed using the Monte Carlo simulation method. The mean inhalation exposure of workers to formaldehyde was 0.636 mg m. The inhalation cancer risk value based on the integrated risk information system for formaldehyde was 4.06×10 ± 3.17×10 (mean ± standard deviation), which exceeded the value reported by the US Environmental Protection Agency. An unacceptable carcinogenic risk level was found in 75.6% of workers. The highest mean inhalation cancer risk was 6.74×10 (i.e., 6.74 additional cases per 10,000 employees exposed) was found in sizing post employees. The hazard quotient of formaldehyde was 0.311±0.024. The formaldehyde concentration had a considerable effect on the health risk. The findings of this study provide valuable scientific information that supports the development of future policies to enhance the health status of employees in carpet manufacturing plants.
甲醛被国际癌症研究机构归类为明确的致癌物质。据我们所知,目前尚无研究评估地毯制造工厂工人职业暴露于甲醛的健康风险。因此,本研究评估了 2022 年伊朗 67 名地毯制造工厂男性工人职业暴露于甲醛的健康风险。在对工人呼吸区进行个人暴露采样并基于国家职业安全与健康研究所的方法 3500 进行分光光度分析后,定量确定了甲醛的暴露情况。下一步,根据个人暴露于甲醛的情况,评估了致癌和非致癌风险。采用蒙特卡罗模拟方法进行了敏感性分析。工人吸入甲醛的平均暴露量为 0.636mg/m³。基于甲醛综合风险信息系统的吸入癌症风险值为 4.06×10±3.17×10(平均值±标准差),超过了美国环境保护署报告的值。发现 75.6%的工人存在不可接受的致癌风险水平。在上胶岗位工人中发现的平均吸入癌症风险最高,为 6.74×10(即每 10,000 名暴露员工中增加 6.74 例)。甲醛的危害商为 0.311±0.024。甲醛浓度对健康风险有显著影响。本研究的结果提供了有价值的科学信息,支持制定未来政策,以提高地毯制造工厂员工的健康状况。