Jaśkiewicz J, Szafran H, Kruszewska M, Brylska U, Król M
Acta Physiol Pol. 1987 Jan-Feb;38(1):22-30.
The concentrations of free fatty acids (FFA), triglycerides (TG), free cholesterol (FC) and estrified cholesterol (EC) as well as the fatty acid composition of TG and EC fractions have been determined in blood serum of 16 infants with coeliac disease. The determinations were carried out three times: after admission and diagnosis but before the initiation of any treatment, after two and after four weeks of a glutene-free diet supplemented with Humana-MCT formula. Before treatment all the infants had weight deficite between 20% and 40%. After two weeks of diet treatment, the concentrations of blood serum FFA and TG decreased as compared to those before the treatment. The highest values of EC were found during the third determination. The composition of fatty acids in TG and EC fractions did not change appreciably in the consecutive determinations. The absence of medium chain-length fatty acids in the studied lipid fractions despite steady supply in the diet suggests efficient metabolization of these acids in the liver. A considerable deficite of linoleic acid appearing in the infants studied before the treatment was not fully compensated during the four weeks of diet treatment.
已对16例乳糜泻婴儿的血清中游离脂肪酸（FFA）、甘油三酯（TG）、游离胆固醇（FC）和酯化胆固醇（EC）的浓度以及TG和EC组分的脂肪酸组成进行了测定。测定进行了三次：入院并诊断后但在开始任何治疗之前、采用不含麸质且添加了Humana-MCT配方奶粉的饮食两周后以及四周后。治疗前，所有婴儿的体重不足20%至40%。饮食治疗两周后，血清FFA和TG的浓度与治疗前相比有所下降。第三次测定时发现EC的最高值。在连续测定中，TG和EC组分中的脂肪酸组成没有明显变化。尽管饮食中持续供应，但在所研究的脂质组分中未发现中链脂肪酸，这表明这些酸在肝脏中有效代谢。治疗前研究的婴儿中出现的亚油酸大量缺乏在四周的饮食治疗期间未得到充分补偿。
