Environmental Health Sciences Division, School of Public Health, University of Minnesota, Minneapolis, USA.
Department of Food Science and Technology, Faculty of Veterinary, Agrifood Campus of International Excellence (ceiA3), University of Cordoba, 14014 Córdoba, Spain.
Int J Food Microbiol. 2022 Dec 16;383:109932. doi: 10.1016/j.ijfoodmicro.2022.109932. Epub 2022 Sep 15.
Invasive listeriosis is a potentially fatal foodborne disease that according to this study may affect up to 32.9 % of the US population considered as increased risk and including people with underlying conditions and co-morbidities. Listeria monocytogenes has been scrutinized in research and surveillance programs worldwide in Ready-to-Eat (RTE) food commodities (RTE salads, deli meats, soft/semi-soft cheese, seafood) and frozen vegetables in the last 30 years with an estimated overall prevalence of 1.4-9.9 % worldwide (WD) and 0.5-3.8 % in the United States (US). Current L. monocytogenes control efforts have led to a prevalence reduction in the last 5 years of 4.9-62.9 % (WD) and 12.4-92.7 % (US). A quantitative risk assessment model was developed, estimating the probability of infection in the US susceptible population to be 10-10,000× higher than general population and the total number of estimated cases in the US was 1044 and 2089 cases by using the FAO/WHO and Pouillot dose-response models. Most cases were attributed to deli meats (>90 % of cases) followed by RTE salads (3.9-4.5 %), soft and semi-soft cheese and RTE seafood (0.5-1.0 %) and frozen vegetables (0.2-0.3 %). Cases attributed to the increased risk population corresponded to 96.6-98.0 % of the total cases with the highly susceptible population responsible for 46.9-80.1 % of the cases. Removing product lots with a concentration higher than 1 CFU/g reduced the prevalence of contamination by 15.7-88.3 % and number of cases by 55.9-100 %. Introducing lot-by-lot testing and defining allowable quantitative regulatory limits for low-risk RTE commodities may reduce the public health impact of L. monocytogenes and improve the availability of enumeration data.
侵袭性李斯特菌病是一种潜在致命的食源性疾病，根据这项研究，美国可能有多达 32.9%被认为是高风险人群的人会受到影响，包括有潜在疾病和合并症的人。在过去的 30 年里，李斯特菌 monocytogenes 一直是全球研究和监测计划的焦点，包括即食（RTE）食品（RTE 沙拉、熟食肉、软/半软奶酪、海鲜）和冷冻蔬菜，全球总体流行率估计为 1.4-9.9%（世界卫生组织）和 0.5-3.8%（美国）。目前的李斯特菌 monocytogenes 控制工作导致过去 5 年流行率降低了 4.9-62.9%（世界卫生组织）和 12.4-92.7%（美国）。开发了一种定量风险评估模型，估计美国易感人群感染的概率比一般人群高 10-10000 倍，使用粮农组织/世卫组织和 Pouillot 剂量反应模型，美国估计病例数为 1044 例和 2089 例。大多数病例归因于熟食肉（超过 90%的病例），其次是即食沙拉（3.9-4.5%）、软质和半软质奶酪和即食海鲜（0.5-1.0%）和冷冻蔬菜（0.2-0.3%）。归因于高风险人群的病例占总病例的 96.6-98.0%，高度易感人群占病例的 46.9-80.1%。通过去除浓度高于 1 CFU/g 的产品批次，污染的流行率降低了 15.7-88.3%，病例数量减少了 55.9-100%。实施逐批检验和为低风险 RTE 商品定义可接受的定量监管限量可能会降低李斯特菌 monocytogenes 的公共卫生影响，并提高计数数据的可用性。
