Wang Xinzhou, Luo Siyan, Tian Guihua, Rao Xiangrong, He Bin, Sun Fuchun
College of Electronic and Information Engineering, Tongji University, Shanghai 200092, China.
Department of Computer Science and Technology, Tsinghua University, Beijing 100084, China.
Evid Based Complement Alternat Med. 2022 Sep 22;2022:5899975. doi: 10.1155/2022/5899975. eCollection 2022.
Tongue diagnosis is a convenient and noninvasive clinical practice of traditional Chinese medicine (TCM), having existed for thousands of years. Prickle, as an essential indicator in TCM, appears as a large number of red thorns protruding from the tongue. The term "prickly tongue" has been used to describe the flow of qi and blood in TCM and assess the conditions of disease as well as the health status of subhealthy people. Different location and density of prickles indicate different symptoms. As proved by modern medical research, the prickles originate in the fungiform papillae, which are enlarged and protrude to form spikes like awn. Prickle recognition, however, is subjective, burdensome, and susceptible to external factors. To solve this issue, an end-to-end prickle detection workflow based on deep learning is proposed. First, raw tongue images are fed into the Swin Transformer to remove interference information. Then, segmented tongues are partitioned into four areas: root, center, tip, and margin. We manually labeled the prickles on 224 tongue images with the assistance of an OpenCV spot detector. After training on the labeled dataset, the super-resolutionfaster-RCNN extracts advanced tongue features and predicts the bounding box of each single prickle. We show the synergy of deep learning and TCM by achieving a 92.42% recall, which is 2.52% higher than the previous work. This work provides a quantitative perspective for symptoms and disease diagnosis according to tongue characteristics. Furthermore, it is convenient to transfer this portable model to detect petechiae or tooth-marks on tongue images.
舌诊是中医一种便捷且无创的临床实践,已存在数千年。芒刺作为中医的一项重要指标,表现为舌面上出现大量红色刺状物。“芒刺舌”这一术语在中医中用于描述气血运行情况,评估疾病状况以及亚健康人群的健康状态。芒刺出现的不同部位和密度表明不同症状。现代医学研究证明,芒刺起源于菌状乳头,菌状乳头增大并突出形成如芒般的尖刺。然而,芒刺识别具有主观性、繁琐且易受外部因素影响。为解决这一问题,提出了一种基于深度学习的端到端芒刺检测工作流程。首先,将原始舌图像输入到Swin Transformer中以去除干扰信息。然后,将分割后的舌头划分为四个区域:舌根、舌中、舌尖和舌边。我们借助OpenCV斑点检测器在224张舌图像上手动标记芒刺。在标记数据集上进行训练后,超分辨率更快区域卷积神经网络(super-resolution faster-RCNN)提取高级舌特征并预测每个单个芒刺的边界框。我们通过实现92.42%的召回率展示了深度学习与中医的协同作用,这比之前的工作高出2.52%。这项工作为根据舌象特征进行症状和疾病诊断提供了定量视角。此外,将这种便携式模型用于检测舌图像上的瘀点或齿痕也很方便。