VanderJagt D J, Garry P J, Bhagavan H N
Am J Clin Nutr. 1987 Aug;46(2):290-4. doi: 10.1093/ajcn/46.2.290.
Plasma ascorbic acid concentrations were determined in eight men and nine women over age 65 on controlled intakes of vitamin C. Plasma ascorbic acid levels were significantly lower in elderly men compared with women for vitamin C intakes ranging from 30 to 280 mg/d. A maximum steady-state level of 1.0 mg/dL (56.78 mumol/L) ascorbic acid was observed in male subjects at an intake of approximately 150 mg/d; female subjects approached a plasma ascorbate level of 1.0 mg/dL (56.78 mumol/L) with an intake of approximately 80 mg/d. At a total vitamin C intake of 60 mg/d, plasma ascorbate levels in men were estimated to be 0.4 mg/dL (22.71 mumol/L) or less. The amount of dehydroascorbic acid in plasma did not vary with intake of vitamin C.
在对维生素C摄入量进行控制的情况下，测定了8名65岁以上男性和9名65岁以上女性的血浆抗坏血酸浓度。对于30至280毫克/天的维生素C摄入量，老年男性的血浆抗坏血酸水平显著低于女性。在男性受试者中，当摄入量约为150毫克/天时，观察到抗坏血酸的最大稳态水平为1.0毫克/分升（56.78微摩尔/升）；女性受试者在摄入量约为80毫克/天时，血浆抗坏血酸盐水平接近1.0毫克/分升（56.78微摩尔/升）。在总维生素C摄入量为60毫克/天时，男性的血浆抗坏血酸盐水平估计为0.4毫克/分升（22.71微摩尔/升）或更低。血浆中脱氢抗坏血酸的量不随维生素C摄入量而变化。
