长期新冠症状的治疗原理——心脏病专家的观点。
The rationale for the treatment of long-Covid symptoms - A cardiologist's view.
作者信息
Schieffer Elisabeth, Schieffer Bernhard
机构信息
Department of Cardiology, Angiology and Critical Care Medicine, University Hospital Marburg (UKGM), Philipps University Marburg, Marburg, Germany.
出版信息
Front Cardiovasc Med. 2022 Sep 15;9:992686. doi: 10.3389/fcvm.2022.992686. eCollection 2022.
The ongoing coronavirus disease 2019 pandemic left us with thousands of patients suffering from neurological, cardiovascular, and psychiatric disorders named post-acute sequelae of COVID-19 or just . In parallel, the vaccination campaigns against SARS-CoV-2 spike protein saved millions of lives worldwide but long-Covid symptoms also appeared rarely following vaccination with a strong overlap to the "canonical" long-Covid symptoms. A therapeutic strategy targeting both, post-VAC and post-SARS-CoV-2 long-Covid symptoms is warranted since exposure to the S-protein either by vaccination or SARS-CoV-2 infection may trigger identical immuno-inflammatory cascades resulting in long-Covid symptoms.
持续的2019冠状病毒病大流行使我们有数千名患者患有神经、心血管和精神疾病，这些疾病被称为COVID-19急性后遗症或简称……。与此同时，针对严重急性呼吸综合征冠状病毒2（SARS-CoV-2）刺突蛋白的疫苗接种运动在全球挽救了数百万人的生命，但接种疫苗后也很少出现长期新冠症状，且与“典型”的长期新冠症状有很大重叠。鉴于通过接种疫苗或SARS-CoV-2感染接触S蛋白可能引发相同的免疫炎症级联反应，从而导致长期新冠症状，因此有必要制定一种针对疫苗接种后和SARS-CoV-2感染后长期新冠症状的治疗策略。
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