Foster J P
J Reprod Fertil. 1978 Sep;54(1):119-21. doi: 10.1530/jrf.0.0540119.
Milked Friesian dairy cows were given 1 or 2 i.v. injections of synthetic LH-RH. The second of 2 injections of LH-RH given 1.5 h apart induced a significantly greater release of LH than did the first. The response to this injection was also significantly greater than that caused by injections given 6 h apart. There was no significant difference between the LH responses to the two injections given 6 h apart. The total LH release produced by the two injections of 100 microgram synthetic LH-RH given 1.5 h apart was significantly greater than that produced by single injection of 200 microgram synthetic LH-RH. It is concluded that there is a short-term increase in the responsiveness of the bovine pituitary gland to LH-RH after an initial LH-RH stimulus.
给泌乳的弗里斯兰奶牛静脉注射1次或2次合成促黄体生成素释放激素（LH-RH）。间隔1.5小时进行的2次LH-RH注射中，第二次注射所诱导的促黄体生成素（LH）释放量显著高于第一次。此次注射所引发的反应也显著大于间隔6小时进行的注射所引发的反应。间隔6小时进行的2次注射所引发的LH反应之间无显著差异。间隔1.5小时注射2次100微克合成LH-RH所产生的LH总释放量显著高于单次注射200微克合成LH-RH所产生的量。得出的结论是，在初次LH-RH刺激后，牛垂体对LH-RH的反应性会有短期增加。
